病原与植物互作中的信号传递以及蛋白翻译调控机制
2017-2022 美国杜克大学生物系, 研究助理
2023-2023 美国杜克大学生物系, 研究科学家
2023-至今 中国科学院微生物研究所,研究员
我们的研究领域主要集中在蛋白质的翻译调控机制,以拟南芥与大豆为研究对象,主要探究病原微生物与植物互作过程中免疫信号传递与蛋白翻译调控之间的关系,并以此为切入点为病原菌防治及农作物抗病应用提供潜在靶点与新的见解。
1. Ma, M., Li, M., Zhou, R., Yu, J., Wu, Y., Zhang, X., Wang, J., Zhou, J*., Liang, X*. (2023). CPR5 positively regulates pattern-triggered immunity via a mediator protein, J. Integr. Plant Biol., 00(00): 1-7.
2. Wang, J., Zhang, X., Greene, G. H., Xu, G., and Dong, X. (2022). PABP/purine-rich motif as an initiation module for cap-independent translation in pattern-triggered immunity. Cell, 185(17): 3186-3200.
3. Wang, X., Ding, Y., Li, Z., Shi, Y., Wang, J., Hua, J., Gong, Z., Zhou, J. M., Yang, S. (2019). PUB25 and PUB26 Promote Plant Freezing Tolerance by Degrading the Cold Signaling Negative Regulator MYB15. Dev. Cell, 2019, 51(2): 222-235.
4. Zhang, D., Wang, J., Wang, D., Kong, Z., Zhou, L., Zhang, G., Gui, Y., Li, J., Huang, J., Wang, B., Liu, C., Yin, C., Li, R., Li, T., Wang, J., Short, D., Klosterman, S., Bostock, R., Dai, X. (2019). Population genomics demystifies the defoliation Verticillium dahliae, New Phytol., 222(2): 1012-1029.
5. Wang, J., Grubb, L., Wang, J., Liang, X., Li, L., Gao, C., Ma, M., Feng, F., Li, M., Li, L., Zhang, X., Yu, F., Xie, Q., Chen, S., Zipfel, C., Monaghan, J., and Zhou, J. (2018). A regulatory module controlling homeostasis of a plant immune kinase. Mol. Cell, 2018, 69(3): 493-504.
6. Liang, X., Ma, M., Zhou, Z., Wang, J., Yang, X., Rao, S., Bi, G., Li, L., Zhang, X., Chai, J., Chen, S., Zhou, J. (2018). Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases. Cell Res., 2018, 28(5): 529-543.
7. Qi, J#., Wang, J#., Gong, Z*., and Zhou, J.M*. (2017). Apoplastic ROS signaling in plant immunity. Curr. Opin. Plant Biol. 38, 92-100.
8. Liang, X., Ding, P., Lian, K., Wang, J., Ma, M., Li, L., Li, M., Zhang, X., Chen, S., Zhang, Y., et al. (2016). Arabidopsis heterotrimeric G proteins regulate immunity by directly coupling to the FLS2 receptor. eLife 5, e13568.
9. Wu, J., Sun Y, Zhao, Y., Zhang, J., Luo, L., Li, M., Wang, J., Yu, H., Liu, G., Yang, L., et al. (2015). Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species. Cell Res. 25, 621-633.
10. Chen, J., Huang, J., Li, N., Ma, X., Wang, J., Liu, C., Liu, Y., Liang, Y., Bao, Y., and Dai, X. (2015). Genome-wide analysis of the gene families of resistance gene analogues in cotton and their response to Verticillium wilt. BMC plant biol. 15, 148.
11. Liu, S., Chen, J., Wang, J., Li, L., Xiao, H., Adam, S., and Dai, X. (2013). Molecular characterization and functional analysis of a specific secreted protein from highly virulent defoliating Verticillium dahliae. Gene 529, 307-316.
1、科技部国家重点研发计划,甘蔗耐旱、抗倒伏基因挖掘与分子调控网络解析,2024/12-2027/11
2、国家自然科学基金面上项目,TOR激酶介导植物免疫信号起始蛋白翻译的分子机制,2025/01-2028/12