代表性论文 (# 共同一作,* 共同通讯)
1. Dai L#, Duan H#, Liu X#, Zhou H#, Duan M, An Y, Yuan L, Zhao X, Xu K, Wu Q, Gao GF. Omicron neutralisation: RBD-dimer booster versus BF.7 and BA.5.2 breakthrough infection. Lancet. 2023 Aug 26;402(10403):687-689.
2. Guo S#, Zheng Y#, Gao Z#, Duan M#, Liu S#, Du P, Xu X, Xu K, Zhao X, Chai Y, Wang P, Zhao Q, Gao GF*, Dai L*. Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine. Cell Discovery. 2023 Jul 28;9(1):79.
3. Xu S#, Duan H#, An Y, Jin X, Duan M, Dubois PM, Huang Y, Xu K, Du H, Kleanthous H*,Dai L*, Gao GF*. Effect of adjuvanting RBD-dimer-based subunit COVID-19 vaccines with Sepivac SWE™. Vaccine. 2023 Apr 24;41(17):2793-2803..
4. Duan M, Duan H, An Y, Zheng T, Wan S, Wang H, Zhao X, Dai L*, Xu K*, Gao GF. A booster of Delta-Omicron RBD-dimer protein subunit vaccine augments sera neutralization of Omicron sub-variants BA.1/BA.2/BA.2.12.1/BA.4/BA.5. Emerging Microbes & Infections. 2023 Dec;12(1):e2179357.
5. Dai L#, Gao L#, Tao L, Hadinegoro SR#, Erkin M#, Ying Z#, He P, Girsang RT, Vergara H, Akram J, Satari HI, Khaliq T, Sughra U, Celi AP, Li F, Li Y, Jiang Z, Dalimova D, Tuychiev J, Turdikulova S, Ikram A, Flores Lastra N, Ding F, Suhardono M, Fadlyana E, Yan J, Hu Z#, Li C#, Abdurakhmonov IY#, Gao GF*, ZF2001 Global Trial Group. Efficacy and Safety of the RBD-Dimer-Based Covid-19 Vaccine ZF2001 in Adults. New England Journal of Medicine. 2022 May 4. doi: 10.1056/NEJMoa2202261.
6. Xu K#, Gao P#, Liu S#, Lu S#, Lei W#, Zheng T#, Liu X, Xie Y, Zhao Z, Guo S, Tang C, Yang Y, Yu W, Wang J, Zhou Y, Huang Q, Liu C, An Y, Zhang R, Han Y, Duan M, Wang S, Yang C, Wu C, Liu X, She G, Liu Y, Zhao X, Xu K, Qi J, Wu G*, Peng X*, Dai L*, Wang P*, Gao GF*. Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2. Cell. 2022. doi:https://doi.org/10.1016/j.cell.2022.04.029
7. An Y#, Li S#, Jin X#, Han JB#, Xu K#, Xu S#, Han Y, Liu C, Zheng T, Liu M, Yang M, Song TZ, Huang B, Zhao L, Wang W, A R, Cheng Y, Wu C, Huang E, Yang S, Wong G, Bi Y, Ke C, Tan W*, Yan J*, Zheng YT*, Dai L*, Gao GF*. A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates. Emerging Microbes & Infections. 2022 Dec;11(1):1058-1071
8. Dai L#*, Xu K#, Li J#, Huang Q, Song J, Han Y, Zheng T, Gao P, Lu X, Yang H, Liu K, Xia Q, Wang Q, Chai Y, Qi J, Yan J*, Gao GF*. Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nature Immunology.2021 Aug;22(8):958-968.
9. Dai L#*, Gao GF*. Viral targets for vaccines against COVID-19.Nature Reviews Immunology. 2021 Feb;21(2).
10. Yang S#, Li Y#, Dai L#, Wang J#, He P#, Li C, Fang X, Wang C, Zhao X, Huang E, Wu C, Zhong Z, Wang F, Duan X, Tian S, Wu L, Liu Y, Luo Y, Chen Z, Li F, Li J, Yu X, Ren H, Liu L, Meng S*, Yan J*, Hu Z*, Gao L*, Gao GF*. Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials. Lancet Infectious Diseases. 2021 Aug;21(8):1107-1119.
11. Huang B#, Dai L#, Wang H, Hu Z, Yang X*, Tan W, Gao GF. Serum sample neutralisation of BBIBP-CorV and ZF2001 vaccines to SARS-CoV-2 501Y.V2. Lancet Microbe. 2021 Jul;2(7):e285
12. Xu K#, An Y#, Li Q#, Huang W#, Han Y, Zheng T, Fang F, Liu H, Liu C, Gao P, Xu S, Liu X, Zhang R, Zhao X, Liu WJ, Bi Y, Wang Y, Zhou D, Wang Q*, Hou W*, Xia Q*, Gao GF*, Dai L*. Recombinant chimpanzee adenovirus AdC7 expressing dimeric tandem-repeat spike protein RBD protects mice against COVID-19. Emerging Microbes & Infections. 2021 Dec;10(1):1574-1588.
13. Zhao X#, Zheng A#, Li D#, Zhang R, Sun H, Wang Q, Gao GF, Han P*, Dai L*.Neutralisation of ZF2001-elicited antisera to SARS-CoV-2 variants. Lancet Microbe. 2021, 2021 Oct;2(10):e494.
14. Dai L#*, Zheng T#, Xu K#, Han Y#, Xu L#, Huang E, An Y, Cheng Y, Li S, Liu M, Yang M, Li Y, Cheng H, Yuan Y, Zhang W, Ke C, Wong G, Qi J, Qin C*, Yan J*, Gao GF*. A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell. 2020 Aug 6;182(3):722-733.e11.
15. Dai L *, Wang Q, Song H, Gao GF*. Zika Virus Envelope Protein and Antibody Complexes. Subcellular Biochemistry (Springer). 2018; 88:147-168.
16. Dai L#, Song J#, Lu X#, Deng YQ#, Musyoki AM, Cheng H, Zhang Y, Yuan Y, Song H, Haywood J, Xiao H, Yan J, Shi Y, Qin CF*, Qi J*, Gao GF*. Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody. Cell Host Microbe. 2016 May 11;19(5):696-704.
17. Wang Q#, Yang H#, Liu X#, Dai L#, Ma T, Qi J, Wong G, Peng R, Liu S, Li J, Li S, Song J, Liu J, He J, Yuan H, Xiong Y, Liao Y, Li J, Yang J, Tong Z, Griffin BD, Bi Y, Liang M, Xu X, Qin C, Cheng G, Zhang X, Wang P, Qiu X, Kobinger G, Shi Y, Yan J*, Gao GF*. Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus. Science Translational Medicine. 2016 Dec 14;8(369):369ra179.
18. Dai L*, Wang Q, Qi J, Shi Y, Yan J, Gao GF*. Molecular basis of antibody-mediated neutralization and protection against flavivirus. IUBMB Life. 2016 Oct;68(10):783-91.
19. Liu J#, Dai L#, Qi J, Gao F, Feng Y, Liu W, Yan J*, Gao GF*. Diverse peptide presentation of rhesus macaque major histocompatibility complex class I Mamu-A 02 revealed by two peptide complex structures and insights into immune escape of simian immunodeficiency virus. Journal of Virology. 2011 Jul;85(14):7372-83.
研究中代表性图片

图:基于抗原结构的新型疫苗设计、开发与转化
参编专著
寨卡病毒与寨卡病毒病,序言,2019,人民卫生出版社