主要从事乳酸菌等益生菌产生的生物活性物质如细菌素的生物合成、代谢调控、作用机制、结构功能等研究; 乳酸菌的益生分子机制研究; 功能乳酸菌在人体肠道及生殖道健康、生态农业及发酵食品等领域的微生物组研究及应用基础研究等。

1.Xia T, Wang T*, Zhang J, Li H, Sun J, Liu S, Yun F, Teng K, Jin S, Wang S, Fu Z, Zhong J*. In-depth proteomic analysis of alfalfa silage inoculated with Lactiplantibacillus plantarum reveals protein transformation mechanisms and optimizes dietary nitrogen utilization. International Journal of Biological Macromolecules. 2025 Apr 3;309(Pt 2):142638. doi: 10.1016/j.ijbiomac.2025.142638.

2. Muhammad Tahir , Tianwei Wang, Jiaqi Zhang, Tianqi Xia, Xian Deng , Xiaofeng Cao, Jin Zhong*. Compound lactic acid bacteria enhance the aerobic stability of Sesbania cannabina and corn mixed silage. BMC Microbiol. 2025 Feb 7;25(1):68. doi: 10.1186/s12866-025-03781-3.

3. Xia T, Huang F, Yun F, Liu Y, Wang T, Wang S, Jin S, Ma X, Wang W, He J, Teng K*, Zhong J*. Lacticaseibacillus rhamnosus LRJ-1 alleviates constipation through promoting gut Bacteroides-derived γ-aminobutyric acid production. Current Research in Food Science. 2024 Nov 12 (9) 100924

4. Xia T, Tahir M, Wang T*, Wang Y, Zhang X, Liu S, Teng K, Fu Z, Yun F, Wang S，Jin S, Hu J, Zhong J*. Lactobacillus cocktail and cellulase synergistically improve the fiber transformation rate in Sesbania cannabina and sweet sorghum mixed silage. Chemical and Biological Technologies in Agriculture 2024 Jun 11:81

5. Jin S, Tahir M, Huang F, Wang T*, Li H，Shi W, Liu Y, Liu W, Zhong J*. Fermentation quality, amino acids profile, and microbial communities of whole-plant soybean silage in response to Lactiplantibacillus plantarum B90 alone or in combination with functional microbes.  Frontiers in Microbiology 2024 Nov 15:1458287.

6. Xia T, Teng K*, Liu Y, Guo Y, Huang F, Tahir M, Wang T, Zhong J*. (2023). A Novel Two-Component Bacteriocin, Acidicin P, and Its Key Residues for Inhibiting Listeria monocytogenes by Targeting the Cell Membrane.  Microbiology Spectrum 2023 Jun 8;e0521022.

7. Li L, Zhang J*, Zhou L, Shi H, Mai H, Su J, Ma X, Zhong J*. (2023). The First Lanthipeptide from Lactobacillus iners, Inecin L, Exerts High Antimicrobial Activity against Human Vaginal Pathogens. Applied and Environmental Microbiology. Mar 29;89(3):e0212322.

8. Teng K, Huang F, Liu Y, Wang Y, Xia T, Yun F, Zhong J*. Food and gut originated bacteriocins involved in gut microbe-host interactions. Critical Reviews in Microbiology 2023 Aug;49(4):515-527. Accepted 24 May 2022.

9. Huang F#, Wang T#, Zhang J, Tahir M, Sun J, Liu Y, Yun F, Xia T, Teng K, Wang J, Zhong J*. Exploring the bacterial community succession and metabolic profiles of Lonicera japonica Thunb. residues during anaerobic fermentation. Bioresource Technology 2022. Jan; 367:128264. doi.org/10.1016/j.biortech.2022.128264. Accepted 30 October 2022

10. Gu S#, Zhang J#, Li L, Zhong J*. Repurposing the endogenous CRISPR-Cas9 system for high-efficiency genome editing in Lacticaseibacillus paracasei. ACS Synthetic Biology 2022 Dec 16;11(12):4031-4042. Accepted 10 November 2022.

11. Li H#, Wang T#, Muhammad T, Zhang J, Sun J, Xia T, Huang F, Liu Y, Liu Z, Zhong J*. Influence of Lactobacillus plantarum inoculation on the silage quality of intercropped Lablab purpureus and sweet sorghum grown in Saline-alkaline region.  Frontiers in Microbiology 2022 Dec 2;13:1059551. Accepted 8 November 2022.

12. Xu H, Wu N, Na N, Sun L, Zhao Y, Ding H, Fang Y, Wang T, Xue Y*, Zhong J*. Fermentation weight loss, fermentation quality, and bacterial community of ensiling sweet sorghum with lactic acid bacterial and different silo density. Frontiers in Microbiology 2022 Nov 14;13:1013913. Accepted 14 October 2022.

13. Xu H, Xue Y*, Na N, Wu N, Zhao Y, Sun L, Moge Q, Wang T, Zhong J*. Fermentation quality, bacterial community, and aerobic stability of ensiling Leymus chinensis with lactic acid bacteria or/and water after long-term storage. Frontiers in Microbiology  2022 Oct 18;13:959018. Accepted 26 September 2022.

14. Wang T, Zhang J, Shi W, Sun J, Xia T, Huang F, Liu Y, Li H, Teng K, Zhong J*. Dynamic Changes in Fermentation Quality and Structure and Function of the Microbiome during Mixed Silage of Sesbania cannabina and Sweet Sorghum Grown on Saline-Alkaline Land. Microbiology Spectrum. 2022 Oct 26;10(5):e0248322. doi: 10.1128/spectrum.02483-22. Epub 2022 Oct 3.

15. Zhang J, Li L, Zhang T, Zhong J*. Characterization of a novel type of glycogen-degrading amylopullulanase from Lactobacillus crispatus. Applied Microbiology and Biotechnology, 2022. Jun;106(11):4053-4064 DOI: 10.1007/s00253-022-11975-2.

16. Xia T#, Wang T#, Sun J, Shi W, Liu Y, Huang F, Zhang J, Zhong J*. Modulation of fermentation quality and metabolome in co-ensiling of Sesbania cannabina and Sweet Sorghum by Lactic Acid Bacterial Inoculants. Frontiers in Microbiology. 2022 Mar 24;13:851271. doi: 10.3389/fmicb.2022.851271.

17. Zhang J#, Li L#, Gu S, Teng K, Ren J, Liu G, Zhong J*. Characterization of a novel fructosyltransferase InuCA from Lactobacillus crispatus that attaches to the cell surface by electrostatic interaction. Applied and Environmental Microbiology. 2022 Feb 22;88(4):e0239921. doi: 10.1128/AEM.02399-21

18. Sun J#, Wang T#, Huang F, Liu Y, Shi W, Ma C, Zhong J*. Silage fermentation: A Potential microbial approach for the forage utilization of Cyperus esculentus L. by-product. Fermentation. 2021 Nov 36(06):675-684

19. Huang F, Teng K, Liu Y, Wang T, Xia T, Yun F, Zhong J*. Nisin Z attenuates lipopolysaccharide-induced mastitis by inhibiting the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways. Journal of Dairy Science. 2022 Apr;105(4):3530-3543. doi: 10.3168/jds.2021-21356

20. Liu Y#, Teng K#, Huang F, Xia T, Zhang J, Wang T, Zhong J*. High-throughput discovery of novel lanthipeptides and producers by metagenomic mining of isolates population (MMIP) from Chinese spicy cabbage. Food research International. 2022 April 154,110991. doi:10.1016/j.foodres.2022.110991

21. Huang F#, Teng K#, Liu Y, Cao Y, Wang T, Ma C, Zhang J, Zhong J*. Bacteriocins: Potential for Human Health. Oxiditive Medicine and Cellular Longevity. 2021 Apr 10;2021:5518825. doi: 10.1155/2021/5518825.

22. Montalbán-López M, Scott T, Ramesh S, …Zhong J…, Donk W*, New developments in RiPP discovery, enzymology and engineering. Natural Product Reports. 2021 Jan 1;38(1):130-239.

23. Yang Zhang, Liyan Zhou, Yan Liu, Xi Zhao, Xianqiang Lian, Jie Zhang, De Zhao, Yujuan Wang, Jin Zhong, Junfeng Wang, Hongli Wang, Linqi Wang#, Yu V. Fu#. A peptide from budding yeast GAPDH serves as a promising antifungal against Cryptococcus neoformans. Microbiol Spectr, 2021. DOI: 10.1128/spectrum.00826-21.

24. Wang T, Teng K, Cao Y, Shi W, Xuan Z, Zhou J, Zhang J, Zhong J*. Effects of Lactobacillus hilgardii 60TS-2, with or without homofermentative Lactobacillus plantarum B90, on the aerobic stability, fermentation quality and microbial community dynamics in sugarcane top silage. Bioresource Technology 2020 (312) 123600. doi: 10.1016/j.biortech.2020.123600

1.国家重点研发计划项目，“大型养殖动物肠道功能微生物组解析与调控”，2000万元；2022YFA1304200；2022.12-2027.11

2. 中国科学院战略性先导（A类）科技专项项目“种草制草养畜关键技术研发及模式构建”，2020.11-2025.10

3. 中国科学院科技帮扶项目，“高效青贮菌剂及青贮技术的产业化推广”，2022.1-2025.12

4. 中国科学院国际伙伴计划项目（中澳CSIRO），“油菜绿色经济: 为畜牧水产培育更加营养和可消化的油菜”，2022.1-2025.12

5. 国家自然科学基金面上项目, “泡菜微生物中细菌素的高通量挖掘及其对泡菜发酵微生物演替及品质的影响”, 2020.1-2023.12

6. 国家自然科学基金面上项目，“女性生殖道益生卷曲乳杆菌抑制白色念珠菌的分子机制”，2016.1-2019.12

7. 公益性行业（农业）专项，“北方秸秆青贮高效复合菌剂开发与微生态系统调控优化技术集成示范”，2015.1-2019.12