我们的研究围绕着微生物和环境展开，通过污染物降解微生物资源获取、降解机制鉴定、关键共性生物学过程解析等来认知微生物如何感知、应答、调控环境，进而推动相关微生物技术的发展。

1. Han Q#, Yang ML#, Liu ZS, Zhao YH, Liu XH, Ai GM, Qin WH, Liu XY*, Li DF*. Simultaneous high molecular weight PAHs degradation and chromate and arsenite detoxification by Altererythrobacter sp. H2. Journal of Hazardous Materials, 2025, 492: 138314.
2. Qin YL, Liang ZL, Ai GM, Liu WF, Tao Y, Jiang CY, Liu SJ*, Li DF*. Heterotrophic nitrification by Alcaligenes faecalis links organic and inorganic nitrogen metabolism. ISME Journal, 2024, 18(1):wrae174.
3. Liu ZS, Wang KH, Han Q, Jiang CY, Liu SJ*, Li DF*. Sphingobium sp. SJ10-10 encodes a not-yet-reported chromate reductase and the classical Rieske dioxygenases to simultaneously degrade PAH and reduce chromate. Journal of Hazardous Materials, 2024, 475: 134889.
4. Zhang ST, Abdelhamid SA, Li DF*, Zhang HJ*.  A hydrogel-modified electrochemical biosensor for the rapid detection of ammonia-nitrogen-resistant bacteria. Science of the Total Environment, 2024, 932: 172828.
5. Guo L#, Wang YH#, Cui R#, Huang Z, Hong Y, Qian JW, Ni B, Xu AM, Jiang CY, Zhulin IB*, Liu SJ*, Li DF*. Attractant and repellent induce opposing changes in the four-helix bundle ligand-binding domain of a bacterial chemoreceptor. PLoS Biology, 2023, 21: e3002429.
6. Wu MR#, Miao LL#, Liu Y#, Qian XX, Hou TT, Ai GM, Yu L, Ma L, Gao XY, Qin YL, Zhu HZ, Du L, Li SY, Tian CL, Li DF*, Liu ZP*, Liu SJ*. Identification and characterization of a novel hydroxylamine oxidase, DnfA, that catalyzes the oxidation of hydroxylamine to N2. Journal of Biological Chemistry, 2022, 298(9): 102372.
7. Chen F#, Liu B#, Guo L, Ge X, Feng W, Li DF*, Zhou H*, Long J*. Biochemical insights into Paf1 complex–induced stimulation of Rad6/Bre1-mediated H2B monoubiquitination. Proceedings of the National Academy of Sciences, 2021, 118(33): e2025291118.

1、国家自然科学基金委员会面上项目，新型直接氨氧化途径中羟胺氧化酶的分子机制及其分布和影响因素研究，2024.01–2027.12。

2、国家自然科学基金委员会重大研究计划培育项目，岩溶地下水系统寡营养条件下的微生物碳代谢研究，2021.01-2023.12。

3、国家自然科学基金委员会面上项目，趋化受体MCP2201介导的趋化激活和抑制的机理研究，2019.01-2022.12。