代表性图片

　　图1. 羊毛硫细菌素bovicin HJ50与受体组氨酸激酶BovK的互作模型

　　图2. 羊毛硫细菌素nisin与受体组氨酸激酶NisK的互作模型

　　图3. 新型细菌素cerecidin的挖掘及生物合成

　　1.  Liu Y^#, Teng K^#, Wang T, Dong E, Zhang M, Tao Y, Zhong J*. Antimicrobial Bacillus velezensis HC6: production of three kinds of lipopeptides and biocontrol potential in maize. Journal of Applied Microbiology 2020 Jan;128(1):242-254

　　2.  Yang X^#, Teng K^#, Li L, Su R, Zhang J, Ai G, Zhong J*. Transcriptional Regulator AcrR Increases Ethanol Tolerance through Regulation of Fatty Acid Synthesis in Lactobacillus plantarum.. Applied and Environmental Microbiology 2019 Oct 30;85(22). pii: e01690-19. doi: 10.1128/AEM.01690-19. Print 2019 Nov 15

　　3.  Qi H#, Li Y#, Yun H#, Zhang T#, Huang Y#, Zhou J, Yan H1, Wei J, Liu Y, Zhang Z, Gao Y, Che Y, Su X, Zhu D, Zhang Y, Zhong J, Yang R. Lactobacillus maintains healthy gut mucosa by producing L-Ornithine. 2019. Communications Biology. 2019 May 8;2:171

　　4.  Wang T^#, Teng K^#, Liu Y, Shi W, Zhang J, Dong E, Zhang X, Tao Y, Zhong J*. Lactobacillus plantarumPFM 105 promotes intestinal development through modulation of gut microbiota in weaning piglets. 2019. Frontiers in Microbiology 2019 Feb 5;10:90.

　　5.  Yang X^#, Teng K^#, Su R, Li L, Zhang T, Fan K, Zhang J, Zhong J*. AcrR and Rex Control Mannitol and Sorbitol Utilization through Their Cross-Regulation of Aldehyde-Alcohol Dehydrogenase (AdhE) in Lactobacillus plantarum. 2019. Applied and Environmental Microbiology Feb 6;85(4). pii: e02035-18

　　6.  Su R, Ni K, Wang T, Yang X, Zhang J, Liu Y, Shi W, Yan L, Jie C, Zhong J*. Effects of ferulic acid esterase-producing Lactobacillus fermentum and cellulase additives on the fermentation quality and microbial community of alfalfa silage. PeerJ. 2019 Oct 8;7:e7712.

　　7.  Wang T^#, Teng K^#, Liu G, Liu Y, Zhang J, Zhang X, Zhang M, Tao Y, Zhong J*. Lactobacillus reuteri HCM2 protects mice against Enterotoxigenic Escherichia coli through modulation of gut microbiota. 2018. Scientific Reports Nov 30;8(1):17485.

　　8.  Zhang L, Teng K, Wang J, Zhang Z, Zhang J, Sun S, Li L, Yang X, Zhong J*. CerR, a single-domain regulatory protein of the LuxR family, promotes cerecidin production and immunity in Bacillus cereus. 2018. Applied and Environmental Microbiology Feb 14; 84(5).

　　9.  Ni K, Zhao J, Zhu B, Su R, Pan Y, Ma J, Zhou G, Tao Y, Liu X, Zhong J*. Assessing the fermentation quality and microbial community of the mixed silage of forage soybean with crop corn or sorghum. 2018. Bioresource Technology Oct; 265:563-567.

　　10. Yang X^#, Teng K^#, Zhang J, Wang F, Zhang T, Ai G, Han P, Bai F, Zhong J*. Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress. Scientific Reports  2017 Jun 1;7(1):2650.

　　11.  Ni K, Wang F, Zhu B, Yang J, Zhou G, Pan Y, Tao Y, Zhong J*. Effects of lactic acid bacteria and molasses additives on the microbial community and fermentation quality of soybean silage. Bioresource Technology 2017 Apr 20;238:706-715.

　　12.  Liu G, Bin P, Wang T, Ren W*, Zhong J, Liang J*, Hu CA, Zeng Z, Yin Y. DNA Methylation and the Potential Role of Methyl-Containing Nutrients in Cardiovascular Diseases. Oxid Med Cell Longev 2017;2017:1670815.

　　13.  Liu G*, Chen S, Zhong J*, Teng K, Yin Y*. Crosstalk between Tryptophan Metabolism and Cardiovascular Disease, Mechanisms, and Therapeutic Implications. Oxidative Medicine and Cellular Longevity2017;2017:1602074.

　　14.  Ge X, Teng K*, Wang J, Zhao F, Zhang J, Zhong J*. Identification of key residues in the NisK sensor region for nisin biosynthesis regulation. Frontiers in Microbiology 2017 Jan 26;8:106.

　　15.  Wang J, Ge X, Zhang L, Teng K, Zhong J*. One-pot synthesis of class II lanthipeptide bovicin HJ50 via an engineered lanthipeptide synthetase.Scientific Reports 2016 Dec 7;6:38630.

　　16.  Ge X, Teng K*, Wang J, Zhao F, Wang F, Zhang J, Zhong J*. Ligand determinants of nisin for its induction activity. Journal of Dairy Science 2016 Jul; 99(7):5022-31.

　　17.  Guo Y, Huang E, Yang X, Zhang L, Yousef A, Zhong J*. Isolation and characterization of a Bacillus atrophaeus strain and its potential use in food preservation. Food control 2016,60: 511–518

　　18.  Zhang J, Zhong J*, The journey of nisin development in China, a natural-green food preservative, Protein Cell 2015, 6(10):709-711

　　19.  Zhao F, Ma H, Lu Y, Teng K, Kang X, Wang F, Yang X, Zhong J*. Complete genome sequence of Lactococcus lactis S0, an efficient producer of nisin, Journal of Biotechnology 2015,198C, 15-16

　　20.  Ma H, Gao Y, Zhao F, Wang J, Teng K, Zhang J, Zhong J*. 2014. Dissecting the catalytic and substrate binding activity of a class II lanthipeptide synthetase BovM. Biochemical and Biophysical Research Communications 450: 1126-1132.

　　21.  Teng K, Zhang J, Zhang X, Ge X, Gao Y, Wang J, Lin Y, Zhong J*. 2014. Identification of ligand specificity determinants in lantibiotic bovicin HJ50 and the receptor BovK, a Multi-transmembrane histidine kinase. Journal of Biological Chemistry 289:9823-9832.

　　22.  Zhang J, Feng Y, Teng K, Lin Y, Gao Y, Wang J, Zhong J*. 2014. Type AII Lantibiotic Bovicin HJ50 with a Rare Disulfide Bond: Structure, Structure-Activity Relationships and Mode of Action. Biochemical Journal 461: 497-508.

　　23.  Wang J, Zhang Li, Teng K, Sun S, Sun Z, Zhong J*. 2014. Cerecidins, novel lantibiotics from Bacillus cereus with potent antimicrobial activity. Applied and Environmental Microbiology 80(8): 2633-2643.

　　24.  Wang J, Gao Y, Teng K, Zhang J, Sun S, Zhong J*. 2014. Restoration of a bioactive lantibiotic suicin from a remnant lan locus of pathogenic Streptococcus suis serotype 2. Applied and Environmental Microbiology 80(3): 1062-1071.

　　25.  Wang J, Ma H, Ge X, Zhang J, Teng K, Sun Z, Zhong J*. 2014. Bovicin HJ50-like lantibiotics, a novel subgroup of lantibiotics featured by an indispensable disulfide bridge. PLoS One 9(5): e97121.

　　26.  Gao Y, Lu Y, Teng K, Chen M, Zheng H, Zhu Y, Zhong J*. 2011. Complete genome sequence of Lactococcus lactis subsp. lactis CV56, a probiotic strain isolated from the vagina of healthy women. Journal of Bacteriology 193(11): 2886-2887.

　　27.  Ni J#, Teng K#, Liu G, Qiao C, Huan L, Zhong J*. 2011. Autoregulation of lantibiotic bovicin HJ50 biosynthesis by two-component signal transduction system BovK/BovR in Streptococcus bovis HJ50. Applied and Environmental Microbiology 77(2): 407-415.

　　28.  Lin Y, Teng K, Huan L, Zhong J *. 2011. Dissection of the bridging pattern of bovicin HJ50, a lantibiotic containing a characteristic disulfide bridge. Microbiological Research 166: 146-154.

　　29.  Zhang Q, Zhong J*, Huan L*. 2011. Expression of Hepatitis B Virus surface antigen determinants in Lactococcus lactis for oral vaccination. Microbiological Research 166: 111-120.

　　30.  Wu S, Feng C, Zhong J*, Huan L*. 2011. Enhanced production of recombinant Nattokinase in Bacillus subtilis by promoter optimization. World Journal of Microbiology and Biotechnology 27: 99-106.

　　31.  Zhang Q, Zhong J*, Liang X, Liu W, Huan L*. 2010. Improvement of human interferon alpha secretion by Lactococcus lactis. Biotechnology Letters 32: 1271-1277.

　　32.  Liang X, Sun Z, Zhong J*, Zhang Q, Huan L*. 2010. Adverse effect of nisin resistance protein on nisin-induced expression system in Lactococcus lactis. Microbiological Research 165: 458-465.

　　33.  Sun Z, Zhong J*, Liang X, Liu J, Chen X, and Huan L*. 2009. Novel mechanism for nisin resistance via proteolytic degradation of nisin by nisin resistance protein (NSR). Antimicrobial Agents and Chemotherapy 53:1964-1973.

　　34.  Liu G, Zhong J*, Ni J, Chen M, Xiao H, Huan L*. 2009. Characteristics of bovicin HJ50 gene cluster in Streptococcus bovis HJ50. Microbiology-SGM 155: 584-593.

　　申请专利 

　　1. 钟瑾，苏日娜，骆爱群，杨小盼，刘亚勇，王天威，陶勇，张杰。“一种利用发酵乳杆菌和纤维素酶制备青贮苜蓿的方法”, 申请号：201910034616.3

　　2. 钟瑾；骆爱群；苏日娜；倪奎奎；陶勇。“一株高产阿魏酸酯酶的发酵乳杆菌及其应用”,申请号：201810737726.1

　　3. 钟瑾，倪奎奎，赵晶云，朱保葛，苏日娜，刘小荣，潘毅，吕新云，周国安，骆爱群，陶勇。“一种饲用大豆与甜高粱混贮的方法”, 申请号：201810455969.6

　　4. 钟瑾，倪奎奎，骆爱群，苏日娜，王天威。“一株高产阿魏酸酯酶的约氏乳杆菌及其应用”, 专利号：ZL201810401778.1

　　5. 钟瑾，张丽，王宁。“启动子增强系统及其在细菌中的应用”, 申请号：201810303643.1

　　6. 钟瑾，张杰，张彤，芦颖。“一株卷曲乳杆菌及其应用”, 专利号：ZL201810022714.0

　　7. 董恩球、钟瑾、张敏、张欣、王天威、滕坤玲、陶勇。“一株具益生特性且拮抗产肠毒性大肠杆菌的罗伊氏乳杆菌及应用”, 申请号：201711474129.6

　　8. 钟瑾、滕坤玲、王天威、陶勇、宫俊杰、张敏、赵煜炜。“一种仔猪源解淀粉芽孢杆菌及其应用”, 申请号：201711212145.8

　　9. 钟瑾，葛晓璇，滕坤玲。“一种提高乳酸菌NICE表达系统中nisin诱导效率的方法”, 专利号：ZL201610280845.X

　　10. 钟瑾，赵方圆。“一种通过糖代谢调控因子提高乳链菌肽nisin的方法”, 专利号：ZL201410575541.7

　　11. 钟瑾，王剑。“一种新型高效的羊毛硫细菌素cerecidin及其应用”, 专利号：ZL201310409912.X

　　12. 钟瑾，芦颖，陈美玲，高涌，滕坤玲。“一株来源于妇女生殖道产细菌素的益生乳酸菌”, 专利号：ZL201110044274.7

　　13. 钟瑾，胡红梅，孙志增，刘家乐，还连栋。 “能与乳链菌肽结合的突变体蛋白及其编码基因与应用”, 专利号：ZL200910092199.4

　　14. 钟瑾，路遥，陈美玲，还连栋。“乳链菌肽突变体蛋白及其编码基因与应用”, 专利号：ZL200910235510.6

　　15. 钟瑾，张秋香，还连栋。 “含有重组人α-2b干扰素的重组乳酸菌及其应用”, 专利号：ZL200910083076.4

　　16. 钟瑾，陈思维，还连栋。 “一种重组人胰岛素及其编码基因与应用”, 专利号：ZL200710121452.5

　　参编专著 

　　1. 《微生物遗传与分子生物学》

　　科学出版社，2019. 8

　　2. 《全株玉米青贮实用技术问答》

　　中国农业出版社，2018. 7

　　3. 《全株玉米青贮制作与质量评价》

　　中国农业科学技术出版社，2016. 3

　　4. 《乳酸细菌现代研究实验技术》，

　　科学出版社，2013.7

　　5. 《益生乳酸细菌——分子生物学及生物技术》

　　科学出版社，2008. 3