RNA沉默和植物抗病机制 研究团组
组长：郭惠珊 博士 研究员 博士生导师
研究方向
1、植物RNA沉默的分子机制及其抗病应用研究； 2、植物与真菌的互作机理及维管束真菌病害的防控策略研究
研究内容及意义
本研究组以模式植物拟南芥、烟草和重要经济作物棉花为寄主材料，以病毒和真菌为病原微生物，围绕植物RNA沉默和miRNA调控途径，以及其他受病原影响的调控途径开展病原微生物－寄主的相互作用研究，剖析植物致病机理。为植物抗病和病害防控提供有效策略。
研究组长
郭惠珊 博士 研究员
电话及传真：010-64804846
电子邮件：guohs#im.ac.cn（请将#换成@）
通讯地址：北京市朝阳区北辰西路1号院3号，
中国科学院微生物研究所
邮编：100101
学习经历
1983.9-1987.7 中山大学生物学，学士
1993.6-1996.6 西班牙马德里大学，博士
工作经历
1987.9-1991.12 中山大学生物工程中心，助教
1992.1-1993.5 西班牙马德里大学"Severo Ochoa"分子生物学中心，Guest Investigator
1997.7-1998.6 西班牙马德里大学国家生物工程中心（CSIC）博士后
1998.7-2003.1 新加坡国立大学分子农业生物学院/淡马锡生命科学研究院Research Fellow
2003.1-2004.6 新加坡国立大学淡马锡生命科学研究院，Acting PI
2004.7-至今 中国科学院"百人计划"，中国科学院微生物所 研究员、博士生导师
获奖
2005年 国家杰出青年科学基金
2015年 国务院政府特殊津贴
2015年 中国科学院大学岗位教授
2015年 中国科学院特聘骨干人才
2015年 中国植物病理学会会士
2017年 中国科学院特聘核心骨干
2017年 中国科学院微生物研究所所长奖教金优秀奖
2020年 中国科学院大学教育教学成果奖二等奖
2021年 中国科学院微生物研究所所长奖教金优秀奖
2022年 第十二届大北农科技奖创新奖
2023年 第九届首都民族团结进步奖
2023年 中国科学院优秀共产党员
2024年 中国科学院微生物研究所所长奖教金优秀奖
学术兼职
中国植物病理学会第十二届理事会常务理事
FEMS Microbiology Reviews Editor 2019-
工作人员
赵建华 项目研究员 zhao_jian_hua#hotmail.com
高 峰 副研究员 gaof-h#im.ac.cn
金 芸 助理研究员 jiny#im.ac.cn
房媛媛 高级工程师 fangyy#im.ac.cn
在读研究生和全职博士后
博士生 刘清艳 女 2019
博士生 田 文 女 2022
硕士生 帅 青 女 2023
硕士生 郭仟葉 女 2024
博士后 李 洁 女 2021
博士后 张博森 男 2022
博士后 陈汝斌 女 2024
已培养学生博士后
博士 段成国 2008年
博士 杜全生 2008年
博士 何祥凤 2009年
博士 应晓宝 2010年
硕士 李 焱 2010年
博士 朱 慧 2011年
博士 周邦军 2012年
博士 徐 宁 2012年
博士 房媛媛 2013年
博士 冯 镭 2013年
博士 赵 盼 2014年
博士 赵建华 2015年
博士 汪晶晶 2015年
博士 赵云龙 2016年
博士 倪 浩 2016年
博士 张 涛 2016年
博士 周婷婷 2016年
硕士 杜 璇 2017年
博士 陈中祺 2018年
硕士 马晓薇 2018年
博士 刘晓兰 2019年
博士 王 胜 2019年
博士 崔 辰 2020年
硕士 尚靖芸 2020年
博士 李 洁 2021年
博士 武雪明 2022年
博士 张博森 2022年
硕士 温汉光 2023年
博士 吴华伟 2024年
硕士 吕弘毅 2024年
博士 刘传慧 2024年
硕士 谌 婷 2025年
博士后 杨丽萍 2012年
博士后 梁祥修 2018年
博士后 高 峰 2020年
代表性论文（*通讯作者, #共同第一作者)
Chen, T., Tian, W., Shuai, Q., Wen, H.G.,Guo, H. S.,Zhao, J. H.* (2025) Microbe-induced gene silencing of fungal gene confers efficient resistance against Fusarium graminearum in maize.aBIOTECH.
Tian, W.#, Zhang, T.#, Zhao, J. H.#, Dong, Y. M., Li, Y. Z., Zhao, Z. Q., Gao, F., Wu, X. M., Zhang, B. S., Fang, Y. Y., Xie, Z. M.*, Guo, H. S.*(2025) HIGS-mediated crop protection against cotton aphids. Plant Biotechnol J 23(3):692-694.
Liu, C.#, Cui, C.#, Zhou, G., Gao, F., Zhao, J., Guo, H.*, Jin, Y.*(2025) The endocytic pathway for absorption of exogenous RNAs in Verticillium dahliae. mLife 4(1):45-54.
Li, J.#, Tian, W.#, Chen, T., Liu, Q. Y., Wu, H. W., Liu, C. H., Fang, Y. Y., Guo, H. S., Zhao, J. H.*(2024) N(6)-methyladenosine on the natural antisense transcript of NIA1 stabilizes its mRNA to boost NO biosynthesis and modulate stomatal movement. Mol Plant 18(1):151-165.
Li, J., Zhang, B. S., Wu, H. W., Liu, C. L., Guo, H. S., Zhao, J. H.*(2024) The RNA-binding domain of DCL3 is required for long-distance RNAi signaling. aBIOTECH 5(1):17-28.
Zhao, Jian-Hua, Liu, Qing-Yan, Xie, Zong-Ming, Guo, Hui-Shan.*(2024) Exploring the challenges of RNAi-based strategies for crop protection. Advanced Biotechnology 2(3):23.
Wen Tian#, Ting Chen#, Qingyan Liu, Bosen Zhang, Huishan Guo*, Jianhua Zhao.*( 2024) Advances in the mechanisms and applications of RNA silencing in crop protection. Hereditas(Beijing) 46(4): 266-278.
ZHAO Jian-hua, GAO Feng, LIU Qing-yan, GUO Hui-shan.* (2024) RNA Silencing Efficiency Affected by RNA Structure. Biotechnology Bulletin 40(10): 19-29.
Wu, X. M.#, Zhang, B. S.#, Zhao, Y. L.#, Wu, H. W., Gao, F., Zhang, J., Zhao, J. H.*, Guo, H. S.*(2023) DeSUMOylation of a Verticillium dahliae enolase facilitates virulence by derepressing the expression of the effector VdSCP8. Nat Commun 14(1):4844.
Wen, H. G.#, Zhao, J. H.#*, Zhang, B. S., Gao, F., Wu, X. M., Yan, Y. S., Zhang, J., Guo, H. S.*(2023) Microbe-induced gene silencing boosts crop protection against soil-borne fungal pathogens. Nat Plants 9(9): 1409-1418.
Liu, Q. Y.#, Li, Y. C.#, Wu, H. W., Zhang, B. S., Liu, C. H., Gao, Y., Guo, H. S., Zhao, J. H.*(2023) Hyphopodium-Specific Signaling Is Required for Plant Infection by Verticillium dahliae. Journal of Fungi 9(4).
Zhao, J. H., Guo, H. S.*(2022) RNA silencing: From discovery and elucidation to application and perspectives. J Integr Plant Biol 64(2): 476-498.
Zhang, T., Zhao, J. H., Fang, Y. Y., Guo, H. S.*, Jin, Y. *(2022) Exploring the Effectiveness and Durability of Trans-Kingdom Silencing of Fungal Genes in the Vascular Pathogen Verticillium dahliae. Int J Mol Sci 23(5).
Zhang, B. S., Li, Y. C.,Guo, H. S.*,Zhao, J. H.* (2022)Verticillium dahliae Secretes Small RNA to Target Host MIR157d and Retard Plant Floral Transition During Infection. Front Plant Sci 13:847086
Zhao, J.H., Liu, Q.Y., Guo, H.S.* (2021) Trans-kingdom RNAs and their fates in recipient cells: advances, utilization, and perspectives. Plant Communications 2:100167.
Jin, Y.*, Zhao, J.H., Guo, H.S. (2021)Recent advances in understanding plant antiviral RNAi and viral suppressors of RNAi. Current opinion in virology 46:65-72.
Chen, Z. Q., Zhao, J. H., Chen, Q., Zhang, Z. H., Li, J., Guo, Z.,Xie, Q., Ding, S. W., Guo, H. S.* (2020)DNA Geminivirus Infection Induces an Imprinted E3 Ligase Gene to Epigenetically Activate Viral Gene Transcription. Plant Cell 32(10), 3256-3272.
Wang, S.#, Wu, X.M.#, Liu, C.H., Shang, J.Y., Gao, F., and Guo, H.S.* (2020)Verticillium dahliae chromatin remodeling facilitates the DNA damage repair in response to plant ROS stress. PLoS Pathog16(4), e1008481.
Cui, C.#, Wang, J.J.#, Zhao, J.H.#, Fang, Y.Y, He, X.F., Guo, H.S.*, Duan, C.G.*(2020). A Brassica miRNA Regulates Plant Growth and Immunity through Distinct Modes of Action. Molecular Plant13(2): 231-245.
Gao, F.#, Zhang, B.S.#, Zhao, J.H., Huang, J.F., Jia, P.S., Wang, S., Zhang, J., Zhou, J.M., Guo, H.S.*（2019）Deacetylation of chitin oligomers increases virulence in soil-borne fungal pathogens. Nature Plants 5(11): 1167-1176.
Zhao, J. H., Guo, H.S.*（2019）.Trans-kingdom RNA interactions drive the evolutionary arms race between hosts and pathogens. Curr Opin Genet Dev 58-59:62-69.
Liu, X.L., Zhao, J.H., Guo, H.S.*（2019）.IBM1-dependent H3K9 demethylation enables self-silencing of an exogenous silencer for the non-cell autonomous silencing of an endogenous target gene. J Genet Genomics 46（3）：149-153.
Jin, Y., Zhao, J. H., Zhao, P., Zhang, T., Wang, S., Guo, H.S.*. （2019）A fungal milRNA mediates epigenetic repression of a virulence gene in Verticillium dahliae. Philos Trans R Soc Lond B Biol Sci 374（1767）：20180309.
Zhao, J. H., Liu, X. L., Fang, Y. Y., Fang, R. X., Guo, H.S.*.（2018）CMV2b-Dependent Regulation of Host Defense Pathways in the Context of Viral Infection. Viruses 10（11).
Qin, J., Wang, K., Sun, L., Xing, H., Wang, S., Li, L., Chen, S., Guo, H.S.*, and Zhang, J.* (2018). The plant specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity. eLife 7.
Jin, Y.#, Zhao, P.#, Fang, Y.Y., Gao, F., Guo, H.S.*, and Zhao, J.H.* (2018). Genome-wide profiling of sRNAs in the Verticillium dahliae-infected Arabidopsis roots. Mycology, 1-11.
Hua,C.L.#, Zhao, J.H.#, and Guo, H.S.* (2018). Trans-kingdom RNA silencing in Plant–Fungal Pathogen Interactions. Mol Plant 11, 235-244.
Du, X., Wang, S., Gao, F., Zhang, L., Zhao, J.H.,Guo, H.S.*, and Hua, C.L.* (2017). Expression of pathogenesis-related genes in cotton roots in response to Verticillium dahliae PAMP molecules.Science China. Life sciences60, 852-860.
Jin, Y., Zhang, T., andGuo, H.S.*(2017). Application of host induced gene silencing in crop protection against fungal diseases.Sheng wu gong cheng xue bao = Chinese journal of biotechnology33, 161-169.
Zhang, L.S.#, Ni, H.#, Du, X., Wang, S., Ma, X.W., Nurnberger, T.,Guo, H.S.*, and Hua, C.L.* (2017). The Verticillium-specific protein VdSCP7 localizes to the plant nucleus and modulates immunity to fungal infections.The New phytologist215, 368-381.
Zhao, Y.L.*, Zhang, T., andGuo, H.S. (2017). Penetration Assays, Fungal Recovery and Pathogenicity Assays for Verticillium dahliae.Bio-Protocol7.
Zhou, T.T., Zhao, Y.L., and Guo, H.S.* (2017). Secretory proteins are delivered to the septin-organized penetration interface during root infection by Verticillium dahliae. PLoS pathogens 13, e1006275.
Fang, Y.Y.#, Zhao, J.H.#, Liu, S.W., Wang, S., Duan, C.G., andGuo, H.S.*(2016). CMV2b-AGO Interaction Is Required for the Suppression of RDR-Dependent Antiviral Silencing in Arabidopsis.Frontiers in Microbiology7, 1329.
Lv, D.Q.#, Liu, S.W.#, Zhao, J.H., Zhou, B.J., Wang, S.P.,Guo, H.S., and Fang, Y.Y. * (2016). Replication of a pathogenic non-coding RNA increases DNA methylation in plants associated with a bromodomain-containing viroid-binding protein.Scientific reports6, 35751.
Wang, S., Xing, H., Hua, C.,Guo, H.S.*, and Zhang, J.* (2016). An improved single-step cloning strategy simplifies the Agrobacterium tumefaciens-mediated transformation (ATMT)-based gene disruption method in Verticillium dahliae.Phytopathology.
Zhang, T., Jin, Y., Zhao, J.H., Gao, F., Zhou, B.J., Fang, Y.Y., andGuo, H.S.*(2016). Host-Induced Gene Silencing of the Target Gene in Fungal Cells Confers Effective Resistance to the Cotton Wilt Disease Pathogen Verticillium dahliae.Mol Plant9, 939-942.
Zhang, T.#, Zhao, Y.L.#, Zhao, J.H.#, Wang, S., Jin, Y., Chen, Z.Q., Fang, Y.Y., Hua, C.L., Ding, S.W., andGuo, H.S.*(2016). Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen.Nature plants2, 16153.
Zhao, J.H.*, Fang, Y.Y., Duan, C.G., Fang, R.X., Ding, S.W., andGuo, H.S.*(2016). Genome-wide identification of endogenous RNA-directed DNA methylation loci associated with abundant 21-nucleotide siRNAs in Arabidopsis.Scientific reports6, 36247.
Zhao, J.H., Hua, C.L., Fang, Y.Y., andGuo, H.S.*(2016). The dual edge of RNA silencing suppressors in the virus-host interactions.Current opinion in virology17, 39-44.
Zhao, Y.L., Zhou, T.T., andGuo, H.S.*(2016). Hyphopodium-Specific VdNoxB/VdPls1-Dependent ROS-Ca2+Signaling Is Required for Plant Infection by Verticillium dahliae.PLoS pathogens12, e1005793.
Fang, Y.Y., Smith, N.A., Zhao, J.H., Lee, J.R.,Guo, H.S., and Wang, M.B.* (2015). Cloning and profiling of small RNAs from cucumber mosaic virus satellite RNA.Methods in molecular biology1236, 99-109.
Jin, Y., andGuo, H.S.*(2015). Transgene-induced gene silencing in plants.Methods Mol Biol105-117.
Shen, W.X., Au, P.C., Shi, B.J., Smith, N.A., Dennis, E.S.,Guo, H.S., Zhou, C.Y., and Wang, M.B.* (2015). Satellite RNAs interfere with the function of viral RNA silencing suppressors.Front Plant Sci281.
Wang, J.J., Zhang, L., andGuo, H.S.*(2015). Arabidopsis Leaf Explant Culture. Bio-Protocol 5(22).
Wang, J.J., andGuo, H.S.*(2015). Cleavage of INDOLE-3-ACETIC ACID INDUCIBLE28 mRNA by microRNA847 upregulates auxin signaling to modulate cell proliferation and lateral organ growth in Arabidopsis.The Plant Cell574-590.
Zahid, K.#, Zhao, J.H.#, Smith, N.A., Schumann, U., Fang, Y.Y., Dennis, E.S., Zhang, R.,Guo, H.S.*, and Wang, M.B.* (2015). Nicotiana small RNA sequences support a host genome origin of cucumber mosaic virus satellite RNA.PLoS genetics11, e1004906.
Zhao, P., Zhao, Y.L., Jin, Y., Zhang, T., andGuo, H.S.* (2014). Colonization process of Arabidopsis thaliana roots by a green fluorescent protein-tagged isolate of Verticillium dahliae.Protein & cell5, 94-98.
Feng, L.#, Duan, C.G.#, andGuo, H.S.*(2013). Inhibition of in vivo Slicer activity of Argonaute protein 1 by the viral 2b protein independent of its dsRNA-binding function.Molecular plant pathology14, 617-622.
Yang, L.P., Fang, Y.Y., An, C.P., Dong, L., Zhang, Z.H., Chen, H., Xie, Q., andGuo, H.S.*(2013). C2-mediated decrease in DNA methylation, accumulation of siRNAs, and increase in expression for genes involved in defense pathways in plants infected with beet severe curly top virus.The Plant journal73, 910-917.
Duan, C.G.#, Fang, Y.Y.#, Zhou, B.J., Zhao, J.H., Hou, W.N., Zhu, H., Ding, S.W., andGuo, H.S.*(2012). Suppression of Arabidopsis ARGONAUTE1-mediated slicing, transgene-induced RNA silencing, and DNA methylation by distinct domains of the Cucumber mosaic virus 2b protein.The Plant cell24, 259-274.
Duan, C.G., Wang, C.H., andGuo, H.S.*(2012). Application of RNA silencing to plant disease resistance.Silence3, 5.
Xu, N., Li, Y., Zhao, Y.T., Guo, L., Fang, Y.Y., Zhao, J.H., Wang, X.J., Huang, L., andGuo, H.S.*(2012). Identification and characterization of small RNAs in the hyperthermophilic archaeon Sulfolobus solfataricus.PloS one7, e35306.
Zhou, B.J., Jia, P.S., Gao, F., andGuo, H.S.*(2012). Molecular characterization and functional analysis of a necrosis- and ethylene-inducing, protein-encoding gene family from Verticillium dahliae.Molecular plant-microbe interactions : MPMI25, 964-975.
Zhu, H., andGuo, H.S.*(2012). The role of virus-derived small interfering RNAs in RNA silencing in plants.Science China. Life sciences55, 119-125.
Dong, L., Liu, M., Fang, Y.Y., Zhao, J.H., He, X.F., Ying, X.B., Zhang, Y.Y., Xie, Q., Chua, N.H., andGuo, H.S.*(2011). DRD1-Pol V-dependent self-silencing of an exogenous silencer restricts the non-cell autonomous silencing of an endogenous target gene.The Plant journal68, 633-645.
Hou, W.N., Duan, C.G., Fang, R.X., Zhou, X.Y., andGuo, H.S.*(2011). Satellite RNA reduces expression of the 2b suppressor protein resulting in the attenuation of symptoms caused by Cucumber mosaic virus infection.Molecular plant pathology12, 595-605.
Zhang, Z., Chen, H., Huang, X., Xia, R., Zhao, Q., Lai, J., Teng, K., Li, Y., Liang, L., Du, Q., Zhou, X.,Guo, H., and Xie, Q.* (2011). BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis.The Plant cell23, 273-288.
Zhu, H., Duan, C.G., Hou, W.N., Du, Q.S., Lv, D.Q., Fang, R.X., andGuo, H.S.*(2011). Satellite RNA-derived small interfering RNA satsiR-12 targeting the 3' untranslated region of Cucumber mosaic virus triggers viral RNAs for degradation.Journal of virology85, 13384-13397.
Chen, H., Zhang, Z., Teng, K., Lai, J., Zhang, Y., Huang, Y., Li, Y., Liang, L., Wang, Y., Chu, C.,Guo, H., and Xie, Q.* (2010). Up-regulation of LSB1/GDU3 affects geminivirus infection by activating the salicylic acid pathway.The Plant journal62, 12-23.
Gao, F.#, Zhou, B.J.#, Li, G.Y., Jia, P.S., Li, H., Zhao, Y.L., Zhao, P., Xia, G.X., andGuo, H.S.*(2010). A glutamic acid-rich protein identified in Verticillium dahliae from an insertional mutagenesis affects microsclerotial formation and pathogenicity.PloS one5, e15319.
Li, Y., Liu, X., Huang, L.,Guo, H.S.*, and Wang, X.J.* (2010). Potential coexistence of both bacterial and eukaryotic small RNA biogenesis and functional related protein homologs in Archaea.Journal of Genetics and Genomics37, 493-503.
Liu, L.J., Zhang, Y.Y., Tang, S.Y., Zhao, Q.Z., Zhang, Z.H., Zhang, H.W., Dong, L.,Guo, H.S., and Xie, Q.* (2010). An efficient system to detect protein ubiquitination by agroinfiltration in Nicotiana benthamiana.The Plant journal61, 893-903.
Teng, K.L., Chen, H., Lai, J.B., Zhang, Z.H., Fang, Y.Y., Xia, R., Zhou, X.P.,Guo, H.S., and Xie, Q.* (2010). Involvement of C4 protein of beet severe curly top virus (family Geminiviridae) in virus movement.PloS one5, e11280.
Wang, W.Q., Wu, Y.R., Li, Y., Xie, J.Y., Zhang, Z.H., Deng, Z.Y., Zhang, Y.Y., Yang, C.P., Lai, J.B., Zhang, H.W., Bao, H.Y., Tang, S.Y., Yang, C.W., Gao, P., Xia, G.X.,Guo, H.S., and Xie, Q. *(2010). A large insert Thellungiella halophila BIBAC library for genomics and identification of stress tolerance genes.Plant molecular biology72, 91-99.
Ying, X.B., Dong, L., Zhu, H., Duan, C.G., Du, Q.S., Lv, D.Q., Fang, Y.Y., Garcia, J.A., Fang, R.X., andGuo, H.S.*(2010). RNA-dependent RNA polymerase 1 from Nicotiana tabacum suppresses RNA silencing and enhances viral infection in Nicotiana benthamiana.The Plant cell22, 1358-1372.
Lai, J.B., Chen, H., Teng, K.L., Zhao, Q.Z., Zhang, Z.H., Li, Y., Liang, L., Xia, R., Wu, Y.R.,Guo, H.S., and Xie, Q.* (2009). RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle.The Plant journal57, 905-917.
Zheng, N.Y., Xia, R., Yang, C.W., Yin, B., Li, Y., Duan, C.G., Liang, L.,Guo, H.S., and Xie, Q.*(2009). Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice.Vaccine27, 5001-5007.
Duan, C.G., Wang, C.H., Fang, R.X., andGuo, H.S.*(2008). Artificial MicroRNAs highly accessible to targets confer efficient virus resistance in plants.Journal of virology82, 11084-11095.
He, X.F., Fang, Y.Y., Feng, L., andGuo, H.S.*(2008). Characterization of conserved and novel microRNAs and their targets, including a TuMV-induced TIR–NBS–LRR class R gene-derived novel miRNA in Brassica.FEBS letters582, 2445-2452.
Zhang, Y.Y., Li, Y., Gao, T., Zhu, H., Wang, D.J., Zhang, H.W., Ning, Y.S., Liu, L.J., Wu, Y.R., Chu, C.C.,Guo, H.S., and Xie, Q.* (2008). Arabidopsis SDIR1 enhances drought tolerance in crop plants.Bioscience, biotechnology, and biochemistry72, 2251-2254.
Du, Q.S.#, Duan, C.G.#, Zhang, Z.H.#, Fang, Y.Y., Fang, R.X., Xie, Q., andGuo, H.S.*(2007). DCL4 targets Cucumber mosaic virus satellite RNA at novel secondary structures.Journal of virology81, 9142-9151.
Zhang, Y.Y., Yang, C.W., Li, Y., Zheng, N.Y., Chen, H., Zhao, Q.Z., Gao, T.,Guo, H.S., and Xie, Q.* (2007). SDIR1 is a RING finger E3 ligase that positively regulates stress-responsive abscisic acid signaling in Arabidopsis.The Plant cell19, 1912-1929.
Zhang, Z.H., Xie, Q., andGuo, H.S.*(2007). Antiviral defense in plants.Plant Viruses1, 21-26.
Xie, Q., andGuo, H.S.*(2006). Systemic antiviral silencing in plants.Virus research118, 1-6.
Guo, H.S., Xie, Q., Fei, J.F., and Chua, N.H*. (2005). MicroRNA directs mRNA cleavage of the transcription factor NAC1 to downregulate auxin signals for arabidopsis lateral root development. The Plant cell 17, 1376-1386.
代表性图片
利用跨界RNAi创制抗蚜棉花新种质。（Plant Biotechnol J 2025）
发现微生物种间RNAi并构建新型作物病害防控技术体系。（Nature plants 2023）
发现“植物-真菌跨界抗病RNAi”新途径。（Nature plants 2016）
实验室合影
