虫媒微生物与宿主互作 研究组
组长：叶健 博士 研究员 博士生导师
研究方向
1. 病原微生物—媒介昆虫—宿主三者互作机制解析；
2. 植物抵御病原感染免疫网络解析；
3. 虫媒柑橘黄龙病的宿主抗病机制及抗病生物技术
研究内容及意义
自然条件下大多病毒借助虫媒传播，不但涉及病毒本身，而且涉及宿主、媒介以及宿主和媒介体内的共生微生物，是一个多因素的复杂生物学过程。目前，世界范围内对虫媒这一类自然宿主生物传播病毒的生物学基础和分子生物学机制的认识依然不足。多数虫媒病毒病至今缺乏像临床药物和疫苗等在内的有效控制手段，在人及动植物领域，对于新发突发虫媒病毒病均只能在暴发后采取被动控制措施。因此，通过多学科交叉合作，系统深入了解虫媒传播病毒生命循环的基本过程和机制迫在眉睫，对虫媒病毒传播的生物学基础和病毒适应跨界宿主机制进行解析，将防控虫媒病毒病的关口前移，研发抗病毒手段势在必行。本研究组在国家自然基金委重大、重点、科技部重点研发及中科院先导等项目大力支持下主要开展以下三个研究方向的工作：
1. 虫媒病毒自然宿主的免疫适应。我们致力于将微观分子生物学、遗传学、媒介昆虫神经生物学技术，发掘、解析和利用抗虫媒病毒相关的代谢重塑机制，发展新型广谱抗病毒化合物。本课题组最近发现入侵双生病毒具有的全新生态学功能，双生病毒感染棉花等植物不仅促进媒介昆虫烟粉虱，而且阻止非介体竞争对手棉铃虫和蚜虫的生态功能，促进双生病毒入侵危害。具体研究成果参见近期代表工作1。
2. 植物抵御虫媒病毒免疫网络解析。最经济有效的防控虫媒植物病毒病的方法是获得抗性品种，解析宿主的抗性机制至关重要。通常实验研究在实验室条件下，植物对一种抗性（病毒或者昆虫）机制，这种研究往往不符合自然条件的病毒传播规律，因为80%的植物病毒在自然条件下由媒介昆虫传播，而作物往往受到虫媒外加病毒的双重复杂胁迫。我们研究植物应对复杂生物胁迫的分子、细胞机制，并通过先进生物技术手段发展抗虫媒病毒传播和传播的新方法、新种质材料，有效防控新发病毒疾病提供了理论基础和绿色应用生物技术，获省部级科技进步奖一项。（参见近期代表工作2）
3. 虫媒柑橘黄龙病的宿主抗病机制及抗病生物技术。目前已知有超过300种细菌病害经由昆虫媒介传播，包括引起黄龙病的柑橘韧皮部杆菌(liberibacter)、螺原体、植原体、苛养木杆菌等，由于多数作物中缺乏抗性基因，主要通过杀灭媒介昆虫来防控。我们通过利用人工智能(AI)结合时空组学等多种前沿方法，高通量从野生作物种质资源中挖掘新型抗病（感病）基因，解析抗病（感病）机制，发展新型抗病生物技术。目前已申请或者获批多项中国和国际发明专利。
研究组长
叶健 博士、研究员、农业室主任
国家杰出青年科学基金获得者（2021）、国家优秀青年科学基金获得者（2015）
电话：64807363（O）；64806195（L）
电子邮件：jianye#im.ac.cn（请将#换成@）
通讯地址：北京市朝阳区北辰西路1号院3号中国科学院微生物研究所H912房间
邮政编码：100101
学习经历
2000–2007 中国科学院微生物研究所，博士
1996–2000 浙江大学农业与生物技术学院，学士
工作经历
2023.08- 农业微生物组学与生物技术研究室，主任
2019-2023.08 农业微生物组学与生物技术研究室，副主任
2017- 中国科学院微生物研究所，研究组长
2014-2017 中国科学院微生物研究所，青年研究组长
2013-2014 新加坡国立大学淡马锡生命科学研究院，Principal Investigator
2011-2013 新加坡国立大学淡马锡生命科学研究院，Biotechnology Manager
2009-2010 新加坡国立大学淡马锡生命科学研究院，Research Fellow
2007-2009 新加坡国立大学淡马锡生命科学研究院，博士后
获奖
浙江大学 竺可桢奖学金
工作人员和特别研究助理
副研究员 赵平芝 女 zhaopz#im.ac.cn
助理研究员 孙艳伟 女 sunyw#im.ac.cn
特别研究助理 梁芷健 女 liangzhj#im.ac.cn
在读研究生
直博生 梁 琳 女 lianglinbrave#163.com
博士生 王宏伟 男 wanghw#im.ac.cn
直博生 高凯星 男 gaokaixing21#mails.ucas.ac.cn
博士生 杨 欢 女 yanghuan21#mails.ucas.ac.cn
直博生 蒋宇航 男 694581204#qq.com
直博生 韦一帆 女 907871609#qq.com
博士生 陈萧月 女 2397241981#qq.com （贵州大学联合培养）
博士生 王萌蓉 女 2308401023#st.gxu.edu.cn （广西大学联合培养）
博士生 尹策策 男 15605196332#163.com （广西大学联合培养）
硕士生 殷宇腾 男 1553194367#qq.com
硕士生 夏秋冬 女 2725921311#qq.com
硕士生 李梦雅 女 2982557486#qq.com
硕士生 朱成容 女 zhucr1991#163.com （河北大学联合培养）
硕士生 刘 奇 男 liuqi211629#petalmail.com （河北大学联合培养）
硕士生 韩 添 男 hantian0899#163.com （广西大学联合培养）
硕士生 刘 晔 女 liuye202020#163.com （广西大学联合培养）
硕士生 李 琼 女 liqiong364#163.com （中国科学技术大学联合培养）
著书章节（*通讯作者, #共同第一作者)
Ma YH, Ye J*. 2017. Lipid biosynthesis and regulation inJatropha curcas, an emerging model for woody energy plants. The Jatropha Genome. Compendium of Plant Genomes. Suguru Tsuchimoto (Ed.) Jatropha. Springer Science Publishers, New York.
Ye J,Wang CM, Yue GH. 2017. Jatropha breeding. The Jatropha Genome. Compendium of Plant Genomes.Suguru Tsuchimoto (Ed.) Jatropha. Springer Science Publishers, New York.
Ye J*, Hong Y, Qu J, Wang CM. 2012.Improvement of Jatropha oil by genetic transformation. Jatropha, Challenges for a New Energy Crop-Genetic Improvement and Biotechnology, vol. 2. Springer Science Publishers, New York.
Qu J,Ye J, Fang RX. 2012. Artificial MicroRNAs for Plant Virus Resistance, Antiviral Resistance in Plants: Methods and Protocols, Methods in Molecular Biology, vol. 894
发表论文（*通讯作者, #共同第一作者)
2024年
Wang D, Yin Y, Zhang X*, Ye J*, An interspecies recombinant sida yellow mosaic China virus isolate and betasatellite cause a leaf curl disease in tobacco in Hainan, China. 2024, 108 (877-886)
Yin Y, Wang D, Wang H, Sun Y, Ye J*. Development and application of sugarcane streak mosaic virus vectors. 2024. Virology, 593, 110028
Wu J, Zhang Y, Li F, Zhang X, Ye J,….Li Y. Plant Virology in the 21st Century in China: Recent Advances and Future Directions. 2024. Journal of Integrative Plant Biology, 66, 579-622
Zhang, X., Wang, D., Zhao, P., Sun, Y., Fang, R.-X., Ye, J*., Near infrared light and PIF4 promote plant antiviral defense by enhancing RNA interference, Plant Communications (2024), doi: https://doi.org/10.1016/j.xplc.2023.100644
2023年
Yin C, Yang L, Xin X, Ye J*, Liu, Q*. Identification of Flavobacterium algoritolerans sp. nov. and Flavobacterium yafengii sp. nov. International Journal of Systematic and Evolutionary Microbiology, 2023;73:006072
Tong X, Zhao JJ, Feng YL, Zou JZ, Ye J, Liu J, Han C, Li D, Wang X. A selective autophagy receptor VISP1 induces symptom recovery by targeting viral silencing suppressors. Nature Communications, 2023 3852
Wang D#, Zhang X#, Yin YT, Chen DX* and Ye J*. First Report of Ludwigia Yellow Vein Vietnam Virus Causing LeafCurling on Tobacco Plants in Hainan Province, China. Plant Disease. 2023. Doi: 10.1094/PDIS-01-23-0034-PDN
Zhang X#, Wang D#, Zhao PZ, Sun YW, Fang RX and Ye J*. Near infrared light and PIF4 promote plant antiviral defense by enhancing RNA interference. Plant Communications. 2023. 100644
Wu X#, Zhang X#, Wang H, Fang R, and Ye J*. Structure-function analyses of coiled-coil immune receptors define a hydrophobic module for improving plant virus resistance. Journal Of Experimental Botany. 2023. 74(5): 1372-1388
2022年
Wang HW#, Wu XJ#, Huang XD, Wei SJ, Lu ZJ and Ye J*. Seed Transmission of Tomato Spotted Wilt Orthotospovirus in Peppers. Viruses. 2022. 14(9): 1873
Wang N#, Zhao PZ#, Wang D#, Mubin M, Fang RX and Ye J*. Diverse Begomoviruses Evolutionarily Hijack Plant Terpenoid-Based Defense to Promote Whitefly Performance. Cells. 2022. 30(12): 149
Chen GM#, Xuan W#, Zhao PZ#, Yao XM, Peng C, Tian YL, Ye J, Wang BX, He J, Chi WC, Yu J, Ge YW, Li J, Dai ZY, Xu DY, Wang CM, Wan JM. OsTUB1 confers salt-insensitivity by interacting with Kinesin13A to stabilize microtubule and ion transporter in rice. 2022. New Phytologist.
https://nph.onlinelibrary.wiley.com/doi/pdf/10.1111/nph.18282
Liu XL, Tian YL, Chi WC, Zhang HZ, Yu J, Chen GM, Wu W, Jiang XZ, Wang SS, Lin ZX, Xuan W, Ye J, Wang BX, Liu Y, Sun ZG, Xu DY, Wang CM, Wan JM. Alternative splicing of OsGS1;1 affects nitrogen-use efficiency, grain development, and amylose content in rice. 2022. The Plant Journal. https://doi.org/10.1111/tpj.15768
Wang D, Bishnu Dawadi, Qu J, Ye J*,Light-Engineering Technology for Enhancing Plant Disease Resistance. Front. Plant Sci. 2022. 12:805614
Wang D, Zhang X, Chen DX, Ye J*.First report of Sida leaf curl virus and associated betasatellite in tobacco. Plant Disease. 2022. 106: 1078
Mubin M, Shabbir A, Nahid N, Liaqat I, Hassan M, Aljarba NH, Al Qahtani A, Fauquet CM,Ye Jand Nawaz-ul-Rehman MS. Patterns of Genetic Diversity among Alphasatellites Infecting Gossypium Species. Pathogens. 2022. 11(7): 763
Nawaz-Ul-Rehman MS, Liaqat I, Nahid N, Saleem F, Alkahtani S, Al Qahtani A,Ye J, Mubin M*. Brazilian Journal of Biology. 2022. 82: e262248
2021年
Zhao PZ, Zhang X, Gong YQ, Wang D, Xu DQ, Wang N, Sun YW, Gao LB, Liu SS, Deng XW, Kliebenstein DJ, Zhou XP, Fang RX, and Ye J*Red-light is an environmental effector for mutualism between begomovirus and its vector whitefly. PLoS Pathogens. 2021. 10.1371/journal.ppat.1008770
Zhao DN, Li YL, Song Y, Yang BJ, Ding X, Gao, F, Ye J, Hao XJ, Zhang Y, Li SL. Ten new nortriterpenes from Euphorbia resinifera and their anti-tomato yellow leaf curl virus activities. Fitoterapia. 2021. 153. 104989
Ye J*, Zhang LL, Zhang X, Wu XJ, Fang RX*. Plant defense networks against insect-borne pathogens. Trends in Plant Science. 2021. 26 (3) 272-287
2020年
Li YL, Zhang Y, Zhao PZ, Hu ZX, Gu YC, Ye J*, Hao XJ*. Two new steroidal alkaloids from the rhizomes of Veratrum nigrum L. and their anti-TYLCV activity. Fitoterapia. 2020. 147. 104731
Wu XJ,Ye J*. Manipulation of Jasmonate Signaling by Plant Viruses and Their Insect Vectors. Viruses. 2020. 12(2), 148
王端，叶健*. 植物病毒资源属性和应用基础研究进展. 生物资源. 2020.42（1）1-8
Wang D, Zhang X, Yao XM, Zhang P, Fang RX, Ye J*. A 7-Amino-Acid Motif of Rep protein essential for virulence is critical for triggering host defense against Sri Lankan cassava mosaic virus. Molecular Plant-Microbe Interactions, 2020. Jan;33(1):78-86 DOI: 1094/MPMI-06-19-0163-FI
2019年
Zhao PZ, Yao XM, Cai CX, Li R, Du J, Sun YW, Wang MY, Zou Z, Wang QM, Kliebenstein DJ , Liu SS, Fang RX and Ye J*.Viruses mobilize plant immunity to deter non-vector insect herbivores. Science Advances. DOI: 10.1126/sciadv.aav9801
Wu XJ#, Xu S#, Zhao PZ, Zhang X, Yao XM, Sun YW，Fang RX, Ye J*.The Orthotospovirus nonstructural protein NSs suppresses plant MYC-regulated jasmonate signaling leading to enhanced vector attraction and performance. PLoS Pathogens. DOI:10.1371/journal.ppat.1007897
Wang N, Zhao PZ, Ma YH, Yao XM, Sun YW, Huang XD, Jin JJ, Zhang YJ, Zhu CX, Fang RX, Ye J*, A whitefly effector Bsp9 targets host immunity regulator WRKY33 to promote performance. Philos. Trans. Roy. Soc. B, 2019.374:20180313
Tang WJ#, Ye J#, Yao XM#, Zhao PZ, Xuan W, Tian YL, Zhang YY, Xu S, An HZ, Chen GM, Yu J, Wu W, Ge YW, Liu XL, Li J, Zhang HZ, Zhao YQ, Yang B, Jiang XZ, Peng C, Zhou C, Terzaghi W, Wang CM* & Wan JM* Genome-wide associated study identified NAC42-activated nitrate transporter conferring high nitrogen use efficiency in rice. Nature Communications. 2019.10(1):5279
2018年
Wang D, Yao, XM, Huang GX, Shi T, Wang GF, Ye J*, First report of Sri Lankan cassava mosaic virus infected cassava in China, Plant Disease 2018, DOI: 10.1094/PDIS-09-18-1590-PDN
Ye J*，Wang CM， Sun YW， Qu J， Mao HZ， Chua NH*. 2018.Overexpression of JcWRI1 in Jatropha elevated seed lipid content and increased seed mass. Frontiers in Plant Sciences, 2018.fpls.2018.01479
2017年
叶 健*，龚雨晴，方荣祥*，病毒—媒介昆虫—植物三者互作研究进展及展望. 中国科学院院刊. 已接收
Sun YW#, Wang CM#,Wang N#, Jiang XY, Mao HZ, Zhu CX, Wen FJ, Wang XH, Lu ZJ, Yue GH, Xu ZF,Ye J*. 2017. Manipulation of Auxin Response Factor 19 affects seed size in the woodyperennial Jatropha curcas. Scientific reports. 7: 40844
Jin JJ,Sun YW#, Qu J, Rahmadsyah, Lim CH, Alfiko Y, NurEstyaBte Rahman, Suwanto A, Yue GH, Wong LS, Chua NH,Ye J*. 2017. Transcriptome and functional analysis reveals hybrid vigor for oil biosynthesis in oil palm. Scientific reports. 7: 439
2016年
Jun Liu#, Shulin Deng#, HW Wu#,Ye J, Hui-Wen Wu, Hai-Xi Sun, and Nam-Hai Chua.2016. CURLY LEAF Regulates Gene Sets Coordinating Seed Size and Lipid Biosynthesis in Arabidopsis. Plant physiology. 17 (1) 424-436
Tang W#, Wu T#,Ye J,Sun J, Jiang Y, Yu J, Tang J, Chen G, Wang C, Wan J.2016. SNP-based analysis of genetic diversity reveals important alleles associated with seed size in rice. BMC Plant Biology 16:93
Wang N#, Yao YM#, Zhu CX, Wen FJ*,Ye J*.2016Towards sustainable protection againstinsect-borneplant viral diseases: phytohormones and beyond. Science Foundation in China. 24(2). Review.Cover
Pingzhi Zhao, Lubomir N. Sokolov,Ye Jian, Cheng-Yi Tang, Jisen Shi, Yan Zhen, Wenzhi Lan, Zhi Hong, Jinliang Qi, Gui-Hua Lu, Girdhar K. Pandey & Yong-Hua Yang.2016The LIKE SEX FOUR2 regulates root development by modulating reactive oxygen species homeostasis in Arabidopsis. Scientific reports. srep28683
Jin JJ#, Lee M#, Bai B#,Sun Yanwei#, Qu J, Rahmadsyah, Yuzer A, Lim CH, Suwanto A, Sugiharti M, Wong LS,Ye Jian*, Chua NH* and Yue GH*.2016Draft genome sequence of an elite Dura palm and whole-genome patterns of DNA variation in oil palm. DNA Research. 23:527
龚雨晴，姚香梅，徐爽，孙艳伟，王宁，马永焕，赵平芝，应晓宝，叶健*. 微生物组学研究与经济作物虫传病害的绿色防控.《植物保护与农产品安全》2016年12月
2015年
Ye J*, Yang J, Sun Y, Zhao P, Gao S, Jung C, Qu J, Fang R, Chua NH*.2015. Geminivirus Activates ASYMMETRIC LEAVES 2 to Accelerate Cytoplasmic DCP2-Mediated mRNA Turnover and Weakens RNA Silencing in Arabidopsis. PLoS pathogens 11:e1005196
Sun YW#, Tee CS#, Ma YH#, Wang G, Yao XM, Ye J*.2015. Attenuation of Histone Methyltransferase KRYPTONITE-mediated transcriptional gene silencing by Geminivirus. Scientific reports 5:16476
Li R, Tee C, Jiang Y, Jiang X, Venkatesh P, Sarojam R, Ye J*. 2015. A terpenoid phytoalexin plays a role in basal defense of Nicotiana benthamiana against Potato virus X. Scientific reports 5:9682
Wang H NQ, Wu HW, Liu J, Ye J, Yu N, Chua NH.2015. Analysis of noncoding transcriptome in rice and maize uncovers roles of conserved lncRNAs associated with agriculture traits. The Plant Journal 84 2: 404-416
Lee M, Xia J, Zou Z, Ye J, Rahmadsyah, Alfiko Y, Jin J, Lieando J, Purnamasari M, Lim C, Suwanto A, Wong L, Chua N, Yue G.2015. A consensus linkage map of oil palm and a major QTL for stem height. Scientific reports 5:8232
2014年
Li R, Weldegergis BT, Li J, Jung C, Qu J, Sun Y, Qian H, Tee C, van Loon JJ, Dicke M, Chua NH, Liu SS, Ye J*.2014. Virulence factors of geminivirus interact with MYC2 to subvert plant resistance and promote vector performance. The Plant cell 26:4991-5008.
Ye J, Qu J, Mao HZ, Ma ZG, Rahman NE, Bai C, Chen W, Jiang SY, Ramachandran S, Chua NH.2014. Engineering geminivirus resistance in Jatropha curcus. Biotechnology for biofuels 7:149
Ye J, Geng Y, Zhang B, Mao H, Qu J, Chua N.2014. The Jatropha FT ortholog is a systemic signal regulating growth and flowering time.Biotechnology for biofuels7:19.
Ye J, Liu P, Zhu C, Qu J, Wang X, Sun Y, Sun F, Jiang Y, Yue G, Wang C.2014. Identification of candidate genesJcARF19andJcIAA9associated with seed size traits in Jatropha. Functional & integrative genomics 14:757-766
Wang G, Sun Y, Xu R, Qu J, Tee C, Jiang X,Ye J*.2014. DNA-A of a highly pathogenicIndian cassava mosaic virusisolated fromJatropha curcascauses symptoms inNicotiana benthamiana. Virus genes 48:402-405
2013年及以前
Wang C, Ye J, Tang W, Liu Z, Zhu C, Wang M, Wan J.2013.Loop nucleotide polymorphism in a putative miRNA precursor associated with seed length in rice (Oryza sativa L.). International journal of biological sciences 9:578-586
Wang CM, Liu P, Sun F, Li L, Liu P, Ye J, Yue GH.2012. Isolation and identification of miRNAs inJatropha curcas. International journal of biological sciences 8:418-429
Qu J,Ye J#, Geng YF, Sun YW, Gao SQ, Zhang BP, Chen W, Chua NH.2012. Dissecting functions ofKATANINandWRINKLED1in cotton fiber development by virus-induced gene silencing. Plant physiology 160:738-748
Ye J*, Hong Y, Qu J, Wang C. 2012.Improvement of Jatropha oil by genetic transformation. Jatropha, Challenges for a New Energy Crop- Genetic Improvement and Biotechnology, vol. 2. Springer Science Publishers, New York
Qu J, Mao HZ, Chen W, Gao SQ, Bai YN, Sun YW, Geng YF, Ye J*.2012. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. Biotechnology for biofuels5:10
Qu J, Ye J, Fang R. 2012.Artificial MicroRNAs for Plant Vir s Resistance, Antiviral Resistance in Plants: Methods and Protocols, Methods in Molecular Biology, vol. 894
Sun F, Liu P, Ye J, Lo LC, Cao S, Li L, Yue GH, Wang CM.2012. An approach for jatropha improvement using pleiotropic QTLs regulating plant growth and seed yield. Biotechnology for biofuels 5:42
Gao S, Qu J, Chua NH, Ye J*.2010. A new strain of Indian cassava mosaic virus causes a mosaic disease in the biodiesel cropJatropha curcas. Archives of virology 155:607-612.
Ye J, Qu J, Zhang JF, Geng YF, Fang RX.2009. A critical domain of theCucumber mosaic virus2b protein for RNA silencing suppressor activity. FEBS letters 583:101-106
Ye J, Qu J, Bui HT, Chua NH.2009. Rapid analysis ofJatropha curcasgene functions by virus-induced gene silencing. Plant biotechnology journal 7:964-976
Qu J,Ye J#, Fang R.2007.Artificial microRNA-mediated virus resistance in plants. Journal of virology81:6690-6699
Xu Y, Ye J#, Liu H, Cheng E, Yang Y, Wang W, Zhao M, Zhou D, Liu D, Fang R.2008. DNA-templated CMV viral capsid proteins assemble into nanotubes. Chemical Communications 1:49-51
Ye J, Liu L, Xue Y, Qu J, Gao G, Fang R.2007.Efficient depletion of multiple SARS-CoV mRNAs by a single small interfering RNA targeting the leader sequence. Progress in Biochemistry and Biophysics 34:1092-1100
国际专利
Jian Ye et al. 一种抗黄龙病植物的培育方法及其应用 (patent application PCT/CN2024/076842)
Jian Ye et al. 一类靶向蛋白降解的多肽及其应用（patent application PCT/CN2024/080958）
Jian Ye, et al. Transcriptome and functional analysis reveals a single gene hybrid vigor for oil yield in oil palm. (US Provisional Patent Application No. 62/082,341)
Jian Ye et al.. A method to enhance plant virus resistance. (United States patent, PCT/SG2014/00003)
Jian Ye et al. Control of pests in plants. (U.S. Patent Application US 2012/02400288A1).
Jian Ye et al. Virus induced gene silencing (VIGS) for functional analysis of genes in cotton. (United States Patent 20120096595)
Jian Ye et al. Functional analysis of Jatropha curcas genes. (United States Patent 20110265233).
Jian Ye et al. Genetic Transformation of Jatropha curcas. (United States Patent 20110247099 A1)
Jian Ye et al. Increasing cotton fiber length by manipulating transcription factor. (United States Patent PCT/SG2012/000139)
Jian Ye et al. Microsomal ω6 Oleate Desaturases. (U.S. patent application PCT/SG2011/000337)
近期代表工作
近期代表工作1：双生病毒操纵植物免疫来抑制非介体昆虫。棉花等植物被双生病感染后，大幅度提宿主植物抵御农业重大害虫—棉铃虫和蚜虫的能力，抗棉铃虫的能力甚至比转杀虫Bt毒基因的抗虫棉还好。进一步研究发现双生病毒利用了高等双子叶植物中保守的免疫抗性基因WRKY20调控的植物的免疫平衡制约机制，显著减少植物维管束组织（双生病毒侵染部位和烟粉虱取食部位）中抗虫化合物的积累，如芥子油苷等，促进传毒介体烟粉虱的种群增长。但是会提高非维管束组织如叶肉细胞中脂肪族芥子油苷水平，并激活植物体内阿司匹林类药物-水杨酸的产生，从而抑制棉铃虫和蚜虫—烟粉虱的主要竞争对手的生长，进一步促进了与烟粉虱的互惠共生，加速了病毒在全球范围内的入侵，造成了严重的粮食安全和生物安全问题。（Science Advances, 2019)
近期代表工作2：光调控病毒-昆虫-植物三者互作的分子机制。利用单色光LED灯箱探究不同光调控植物的抗虫和抗病途径，发现红光通过PIFs蛋白调控萜烯类化合物的合成起到抗虫的作用（图A, PLoS Pathogens, 2021)。红外光通过促进PIF4蛋白积累激活RDR6/AGO1的表达，通过影响RNAi途径调控植物抗病反应（图B, Plant Com, 2023)，以上研究为利用单色LED灯绿色防控虫媒病毒病害提供理论基础。
近期代表工作3：本课题组结合基因组、泛基因组和性状功能分析挖掘甘蔗高产高糖抗病关键调控基因，利用新型基因组编辑技术，突破甘蔗高效基因编辑瓶颈，进行多点多年田间育种评价、大数据辅助品种选育等现代生物技术，快速创制高产量高糖分甘蔗优良新种质，全面提升甘蔗的产量、含糖量和抗逆性，突破甘蔗产业链发展瓶颈的核心种质创建问题，建立高复杂度基因组经济作物育种新范式。
本实验室为学生提供良好的发展平台，有着丰富多彩的生活。
