| 论文题目: | Eryngiolide A, a Cytotoxic Macrocyclic Diterpenoid with an Unusual Cyclododecane Core Skeleton Produced by the Edible Mushroom Pleurotus eryngii |
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| 作者: | Wang, SJ; Li, YX; Bao, L; Han, JJ; Yang, XJ; Li, HR; Wang, YQ; Li, SJ; Liu, HW |
| 联系作者: | Li, HR |
| 刊物名称: | ORGANIC LETTERS |
| 期: | 14 |
| 卷: | 14 |
| 页: | 3672-3675 |
| 年份: | 2012 |
| 影响因子: | 5.862 |
| 论文下载: | |
| 摘要: | Eryngiolide A (1), the first member of C20 diterpenoids with the skeleton deriving from a cyclododecane core fused with two gamma-lactone units, was isolated from the solid culture of the edible mushroom Pleurotus eryngii. The structure of 1 was elucidated by extensive analysis of NMR spectra. Compound 1 exhibited moderate cytotoxicity against two human cancer lines in vitro. |
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