| 论文题目: | Efficient production of L-lactic acid with high optical purity by alkaliphilic Bacillus sp WL-S20 |
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| 作者: | Meng, Y; Xue, YF; Yu, B; Gao, CH; Ma, Y |
| 联系作者: | Ma, YH |
| 刊物名称: | BIORESOURCE TECHNOLOGY |
| 期: | |
| 卷: | 116 |
| 页: | 334-339 |
| 年份: | 2012 |
| 影响因子: | 4.98 |
| 论文下载: | |
| 摘要: | Highly efficient polymer-grade L-lactic acid production was achieved by an alkaliphilic strain Bacillus sp. WL-S20 using inexpensive peanut meal as nitrogen source and sodium hydroxide as neutralizing agent. In multi-pulse fed-batch fermentation of Bacillus sp. WL-S20, a L-lactic acid concentration of 225 g/l with a yield of 99.3% was obtained. In single-pulse fed-batch fermentation, a concentration of 180 g/l was obtained with a yield of 98.6%. No D-isomers of lactic acid were detected. The production of a high concentration of optically pure L-lactic acid by alkaliphilic Bacillus sp. WL-S20, combined with a low-cost nutrient and environment-friendly NaOH-based process, represent a potentially novel way for L-lactic acid production at an industrial scale. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved. |
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