代表性图片

Bacterial spore germination receptors are nutrient-gated ion channels (Science, 2023)

Science, 2023→Genes Dev, 2024→Genes Dev, 2022

The pathway for bacterial spore germination

近期代表性论文

1. Gao Y, Amon JD, Artzi L, Ramírez-Guadiana FH, Cofsky JC, Kruse AC, Rudner DZ. SpoVAF and FigP form an oligomeric ion channel that amplifies nutrient-triggered spore germination. Genes Dev 38, 31-45 (2024).

2. Gao Y, Amon JD, Artzi L, Ramírez-Guadiana FH, Brock KP, Cofsky JC, Marks DS, Kruse AC, Rudner DZ. Bacterial spore germination receptors are nutrient-gated ion channels. Science 380, 387-391, doi:10.1126/science.adg9829 (2023).

Spotlight by Trends in Microbiology: Spore germination receptors - a new paradigm

3. Gao Y, Barajas-Ornelas RDC, Amon JD, Ramírez-Guadiana FH, Alon A, Brock KP, Marks DS, Kruse AC, Rudner DZ. The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination. Genes Dev 36, 634-646, doi:10.1101/gad.349488.122 (2022).

4. Wenzel M, Celik Gulsoy IN, Gao Y, Teng Z, Willemse J, Middelkamp M, van Rosmalen MGM, Larsen PWB, van der Wel NN, Wuite GJL, Roos WH, Hamoen LW. Control of septum thickness by the curvature of SepF polymers. Proc Natl Acad Sci U S A 118, doi:10.1073/pnas.2002635118 (2021).

5. Syvertsson S, Wang B, Staal J, Gao Y, Kort R, Hamoen LW. Different Resource Allocation in a Bacillus subtilis Population Displaying Bimodal Motility. J Bacteriol 203, e0003721, doi:10.1128/jb.00037-21 (2021).

6. Gao Y, Wenzel M, Jonker MJ, Hamoen LW. Free SepF interferes with recruitment of late cell division proteins. Sci Rep 7, 16928, doi:10.1038/s41598-017-17155-x (2017).

7. Syvertsson S, Vischer NO, Gao Y, Hamoen LW. When Phase Contrast Fails: ChainTracer and NucTracer, Two ImageJ Methods for Semi-Automated Single Cell Analysis Using Membrane or DNA Staining. PLoS One 11, e0151267, doi:10.1371/journal.pone.0151267 (2016).

8. Gao Y, Liu C, Ding Y, Sun C, Zhang R, Xian M, Zhao G. Development of genetically stable Escherichia coli strains for poly(3-hydroxypropionate) production. PLoS One 9, e97845, doi:10.1371/journal.pone.0097845 (2014).

9. Gao Y, Feng X, Xian M, Wang Q, Zhao G. Inducible cell lysis systems in microbial production of bio-based chemicals. Appl Microbiol Biotechnol 97, 7121-7129, doi:10.1007/s00253-013-5100-x (2013).

10. Zeng Y, Guo L, Gao Y, Cui L, Wang M, Huang L, Jiang M, Liu Y, Zhu Y, Xiang H, Li D, Zheng Y. Formation of NifA-PII complex represses ammonium-sensitive nitrogen fixation in diazotrophic proteobacteria lacking NifL. Cell Rep 43(7): 114476 (2024). 

11. Zhang X, Liu C, Gao Y, Liu L, Zhang H. The canalization in domesticated yeast: Metabolic traits develop robustness against Hsp90 stress during the evolutionary process. Green Carbon, doi: 10.1016/j.greenca.2024.11.002 (2024).

12. Jiang M, Liu M, Gao Y, Zheng Y. Discovery of a new host for rhizobial symbiont in the ocean. The Innovation Life, 2(3), Article 100077. (2024)

13. Liu C, Li X, Han Y, Li W, Gao Y, Jiang C, Liu Y, Zheng Y. Enhanced pyrite bioleaching through the synergistic interactions between Sulfobacillus thermosulfidooxidans and Alicyclobacillus ferrooxydans. Environ. Technol. Innov. 37, 104005 (2025).