1.     Min Wang, Zhoujie Xie, Shoubin Tang, Ee Ling Chang, Yue Tang, Zhengyan Guo, Yinglu Cui, Bian Wu, Tao Ye, Yihua Chen* (2020) Reductase of mutanobactin synthetase triggers sequential C？C macrocyclization, C？S bond formation, and C？C bond cleavage. Org. Lett. 22:960-964.

　　2.     Yuwei Zhang, Min Wang, Jun Tian, Jia Liu, Zhengyan Guo, Wei Tang, Yihua Chen* (2020) Activation of paulomycin production by exogenous γ-butyrolactone signaling molecules in Streptomyces albidoflavus J1074. Appl. Microbiol. Biotechnol. 104(4):1695-1705. doi:10.1007/s00253-019-10329-9.

　　3.     Tingting Hao, Zhoujie Xie, Min Wang, Liwei Liu, Yuwei Zhang, Weicang Wang, Zhao Zhang, Xuejin Zhao, Pengwei Li, Zhengyan Guo, Shushan Gao, Chunbo Lou, Guodong Zhang, Justin Merritt, Yihua Chen* (2019) An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters. Nat. Commun. 10:3665.

　　4.     Ankanahalli N. Nanjaraj Urs,Yiling Hu, Pengwei Li, Zhiguang Yuchi, Yihua Chen*, Yan Zhang* (2019) Cloning and expression of a nonribosomal peptide synthetase to generate blue rose. ACS Syn. Biol. 8:1698-1704.

　　5.      Junyang Wang, Weishan Wang, Huizhuan Wang, Fang Yuan, Zhen Xu, Keqian Yang, Zilong Li,* Yihua Chen,* Keqiang Fan* (2019) Improvement of stress tolerance and riboflavin production of Bacillus subtilis by introduction of heat shock proteins from thermophilic bacillus strains. Appl. Microbiol. Biotechnol. 103:4455–4465.

　　6.     Tongjian Yang, Keqian Yang, Yihua Chen,* Keqiang Fan* (2019) Characterization of a bi-directional promoter otrRp involved in oxytetracycline biosynthesis. Curr. Microbiol. 76:1264–1269.

　　7.     陈萌, 唐伟, 郭正彦, 陈义华* (2019) L-六碳糖形成机制的研究进展. 微生物学通报 46(7): 1678？1694.

　　8.     Wei Chen, Jun Yao, Jie Meng, Wenjing Han, Yong Tao, Yihua Chen, Yixin Guo, Guizhi Shi, Yang He, Jian-Ming Jin, Shuang-Yan Tang* (2019) Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis. Nat. Commun. 10:960.

　　9.     Luyao Gong, Ming Li, Feiyue Cheng, Dahe Zhao, Yihua Chen, Hua Xiang* (2019) Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica. Nucleic Acids Res.11:2880-5891.

　　10.  Zhengyan Guo, Pengwei Li, Guozhu Chen, Chao Li, Zhenju Cao, Yuwei Zhang, Jinwei Ren, Hua Xiang, Shuangjun Lin, Jianhua Ju, Yihua Chen* (2018) Design and biosynthesis of dimeric alboflavusins with biaryl linkages via regiospecific C-C bond coupling. J. Am. Chem. Soc. 140(51):18009-18015

　　11.  Wei Tang, Zhengyan Guo, Zhenju Cao, Min Wang, Pengwei Li, Xiangxi Meng, Xuejin Zhao, Zhoujie Xie, Wenzhao Wang, Aihua Zhou, Chunbo Lou, Yihua Chen* (2018) D-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B. Proc. Natl. Acad. Sci. USA 115(11): 2818-2823.

　　12.  Chunzhi Gao, Zhengyan Guo, Xingzhong Lu, Haiyan Chen, Liwei Liu, Zhiguo Yu*, Yihua Chen* (2018) Hexaricins, pradimicin-like polyketides from a marine sediment-derived Streptosporangium sp. and their antioxidant effects. J. Nat. Prod. 81:2069？2074.

　　13.  Pengwei Li, Zhengyan Guo, Wei Tang, Yihua Chen* (2018) Activation of three natural product biosynthetic gene clusters from Streptomyces lavendulae CGMCC 4.1386 by a reporter-guided strategy. Syn. Syst. Biotechnol. 3:254–260.

　　14.  Yue Tang, Min Wang, Yong Ding, Jine Li, Yihua Chen* (2018) Improvement of paulomycin stability by addition of paulic acid. Chin. J. Org. Chem. 38:2420-2426.

　　15.  Fangying Song, Ning Liu, Minghao Liu, Yihua Chen, Ying Huang* (2018) Identification and characterization of mycemycin biosynthetic gene clusters in Streptomyces olivaceus FXJ8.012 and Streptomyces sp. FXJ1.235. Mar. Drugs 16:98. DOI:10.3390/md16030098

　　16.  Tianhu Zhao, Yuhuan Zhang, Huijun Wu, Di Wang, Yihua Chen, Mei-Jun Zhu, Luyan Z. Ma* (2018) Extracellular aminopeptidase modulates biofilm development of Pseudomonas aeruginosa by affecting matrix exopolysaccharide and bacterial cell death. Environ. Microbiol. Rep. 10(5):583–593.

　　17.  Dingrong Xue, Fang Tian, Fenghuan Yang, Huamin Chen, Xiaochen Yuan, Ching-Hong Yang, Yihua Chen, Qi Wang, Chenyang He* (2018) Phosphodiesterase EdpX1 promotes Xanthomonas oryzae pv. oryzae virulence, exopolysaccharide production, and biofilm formation. Appl. Environ. Microbiol. 84:e01717- e01718.

　　18.  Xuming Luo, Jidong Cao, Junkai Huang, Zongyi Wang, Zhengyan Guo, Yihua Chen, Shumei Ma, Jun Liu* (2018) Genome sequencing and comparative genomics reveal the potential pathogenic mechanism of Cercospora sojina Hara on soybean. DNA Res. 25:25–37.

　　19.  Xiangxi Meng, Wenzhao Wang, Zhoujie Xie, Pengwei Li, Yue Li, Zhengyan Guo, Yingjian Lu, Jie Yang, Kaile Guan, Zhaoxin Lu, Huarong Tan, Yihua Chen* (2017) Neomycin biosynthesis is regulated positively by AfsA-g and NeoR in Streptomyces fradiae CGMCC 4.7387. Sci China Life Sci. 60(9):980-991.

　　20.  Zhoujie Xie, Zhao Zhang, Zhenju Cao, Meng Chen, Pengwei Li, Weifeng Liu, Hua Qin, Xuejin Zhao, Yong Tao, Yihua Chen* (2017) An external substrate-free blue/white screening system in Escherichia coli. Appl. Microbiol. Biotechnol. 101:3811-3820.

　　21.  谢周杰，张昭，刘力伟，柳孝晨，陈义华* (2017) 变形链球菌中的次级代谢产物及其在口腔生物被膜中的生态功能. 生物工程学报33(9):1547？1554.

　　22.  Zhiguo Zhang, Yue Tang, Min Wang, Yihua Chen* (2017) Synthesis, characterizations and antimicrobial activities of new thiourea derivatives. Microbiology China (微生物学报) 44(6): 1437？1443.

　　23.  Yan-long Yang, Shasha Zhang, Ke Ma, Yuxing Xu, Qiaoqiao Tao, Yihua Chen, Juan Chen, Shunxing Guo, Jinwei Ren, Wenzhao Wang, Yong Tao, Wen-Bing Yin, Hongwei Liu* (2017) Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi. Angew. Chem. Int. Ed. 56:4749 –4752.

　　24.  Guohui Pan, Xiaoqin Gao, Keqiang Fan, Junlin Liu, Bing Meng, Jinmin Gao, Bin Wang, Chaobo Zhang, Hui Han, Guomin Ai, Yihua Chen, Dong Wu, Zhi-Jie Liu*, Keqian Yang* (2017) Structure and function of a C？C bond cleaving oxygenase in atypical angucycline biosynthesis. ACS Chem. Biol. 12(1):142–152.

　　25.  李金娥，王敏，陈义华* (2016) 链丝菌素类抗生素的研究进展. 微生物学报56(3): 363-372.

　　26.  Jine Li，Min Wang，Yong Ding, Yue Tang, Zhiguo Zhang*, Yihua Chen* (2016) Involvement of an octose ketoreductase and two acyltransferases in the biosynthesis of paulomycins. Sci. Rep. 6:21180.

　　27.  Jun Tian, Haiyan Chen, Zhengyan Guo, Ning Liu, Jine Li, Ying Huang, Wensheng Xiang*, Yihua Chen* (2016) Discovery of pentangular polyphenols hexaricins A–C from marine Streptosporangium sp. CGMCC 4.7309 by genome mining. Appl. Microbiol. Biotechnol. 100(9):4189-4199.

　　28.  Liwei Liu, Tingting Hao, Zhoujie Xie, Geoff P. Horsman, Yihua Chen* (2016) Genome mining unveils widespread natural product biosynthetic capacity in human oral microbe Streptococcus mutans. Sci. Rep. 6:37479.

　　29.  Zhengyan Guo, Jine Li, Hua Qin, Min Wang, Xun Lv, Xuebing Li, Yihua Chen* (2015) Biosynthesis of the carbamoylated D-gulosamine moiety of streptothricins: involvement of a guanidino-N-glycosyltransferase and an N-acetyl-D-gulosamine deacetylase. Angew. Chem. Int. Ed. 54(17):5175-5178.

　　30.  Jine Li, Zhoujie Xie, Min Wang, Guomin Ai, Yihua Chen* (2015) Identification and analysis of the paulomycin biosynthetic gene cluster and titer improvement of the paulomycins in Streptomyces paulus NRRL 8115. PLoS One 10(3): e0120542. doi:10.1371/journal.pone.0120542.

　　31.  Pengwei Li, Jine Li, Zhengyan Guo, Wei Tang, Jianshan Han, Xiangxi Meng, Tingting Hao, Yaxin Zhu, Lixin Zhang, Yihua Chen* (2015) An efficient blue-white screening based gene inactivation system for Streptomyces. Appl. Microbiol. Biotechnol. 99:1923–1933.

　　32.  Haiyan Chen, Ning Liu, Ying Huang*, Yihua Chen* (2014) Isolation of an anthrabenzoxocinone 1.264-C from Streptomyces sp. FXJ1.264 and absolute configuration determination of the anthrabenzoxocinones. Tetrahedron: Asymmetry 25:113-116.

　　33.  Jine Li, Zhengyan Guo, Wei Huang, Xiangxi Meng, Guomin Ai, Gongli Tang*, Yihua Chen* (2013) Mining of a streptothricin gene cluster from Streptomyces sp. TP-A0356 genome via heterologous expression. Sci China Life Sci. 56:619-627.

　　34.  Jeremy R. Lohman, Sheng-Xiong Huang, Geoffrey P. Horsman, Paul E. Dilfer, Tingting Huang, Yihua Chen, Evelyn Wendt-Pienkowski, Ben Shen* (2013) Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics. Mol Biosyst. 9:478-491.

　　35.  Jine Li, Lei Li, Chi Feng, Yihua Chen, Huarong Tan* (2012) Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes. Microbial Cell Factories 11:135.

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