Understanding microbial metabolism through integrative modeling

　　报告题目: Understanding microbial metabolism through integrative modeling

　　报 告 人: 廖辰 博士

　　报告人单位: University of Illinois at Urbana-Champaign

　　报告时间: 2015年6月30日(星期二)15:30

　　报告地点: A723会议室

　　主 持 人: 刘双江 研究员

　　报告摘要: Microbial metabolism involves complex, system-level processes implemented via the orchestration of multiple subsystems, including metabolic pathway, gene regulation network, and environmental cues. The complexity and systems nature of the process pose a great challenge to decipher bacterial metabolism in response to environmental stimuli. Mathematical modeling is becoming an indispensible tool for the study of cellular processes but the vast majority of the models focus on specific subsystems and their predictive power is thus limited. Integrative modeling, however, captures the true interdependence between different subsystems and provides a systematic way of interconnecting and bridging those layers.